SCHEMBL3120601

SCHEMBL3120601

COC1(OC)C=CC(C(=O)c2ccccc2)C(O)=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
EPHX1 P07099 4/20 0.35
HTT P42858 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CES1 P23141 2/20 0.34
SRC P12931 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 2/20 0.33
HPGD P15428 2/20 0.33
CYP2C19 P33261 2/20 0.33
MAPK1 P28482 2/20 0.33
LMNA P02545 1/20 0.33
PGR P06401 1/20 0.33
CYP2D6 P10635 1/20 0.33
SLC6A2 P23975 1/20 0.33
PDE4A P27815 1/20 0.33
HRH1 P35367 1/20 0.33
SLC6A3 Q01959 1/20 0.33
PDE4D Q08499 1/20 0.33
ALOX15 P16050 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10823202 0.90 ALDH1A1 (0.33) TSHREPHX1HTTSMN1; SMN2CES1
SCHEMBL11299734 0.86 CA12 (0.38) ALDH1A1MAPTGAAKDM4E
SCHEMBL344146 0.85 HTT (0.38) TSHREPHX1HTTSMN1; SMN2CES1
SCHEMBL9461488 0.85 MAPT (0.35) TSHRHTTSMN1; SMN2CES1ALDH1A1
SCHEMBL8172322 0.84 TSHR (0.35) TSHREPHX1HTTSMN1; SMN2CES1
SCHEMBL9461049 0.84 CES2 (0.47) TSHRSMN1; SMN2CES1ALDH1A1CES2
SCHEMBL180232 0.83 TSHR (0.34) TSHREPHX1HTTSMN1; SMN2CES1
SCHEMBL9732807 0.83 TSHR (0.34) TSHREPHX1HTTSMN1; SMN2CES1
SCHEMBL7855173 0.83 TSHR (0.34) TSHREPHX1HTTSMN1; SMN2CES1
SCHEMBL337246 0.83 LMNA (0.41) TSHRHTTSMN1; SMN2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN claimed
CN-119947692-A Gel composition and oil-in-water composition 株式会社资生堂 2025-05-06 CN disclosed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN disclosed
CN-110770282-A Curable silicone composition, and application and use thereof 莫门蒂夫性能材料股份有限公司 2020-02-07 CN disclosed
WO-2007038454-A9 COMPOSITION AND PROCESS FOR TREATING KERATINOUS SUBSTRATES WITH AT LEAST TWO IMMISCIBLE COSMETIC COMPOSITIONS L'OREAL (FR) 2010-04-01 WO disclosed
EP-1928399-A1 COMPOSITION AND PROCESS FOR TREATING KERATINOUS SUBSTRATES WITH AT LEAST TWO IMMISCIBLE COSMETIC COMPOSITIONS L'Oréal (FR) 2008-06-11 EP disclosed
WO-2007038454-A1 COMPOSITION AND PROCESS FOR TREATING KERATINOUS SUBSTRATES WITH AT LEAST TWO IMMISCIBLE COSMETIC COMPOSITIONS L'OREAL (FR) 2007-04-05 WO disclosed
EP-1372595-A2 PHOTOPROTECTING FORMULATIONS Societe L'Oreal S.A. (FR) 2004-01-02 EP disclosed
WO-2002067885-A2 PHOTOPROTECTING FORMULATIONS SOCIETE L'OREAL S.A. (FR) 2002-09-06 WO disclosed
WO-2002067884-A1 SUNSCREEN FORMULATIONS COMPRISING INTERPOLYMERS SOCIETE L'OREAL S.A. (FR) 2002-09-06 WO disclosed
US-4179432-A 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-12-18 US disclosed
US-4131463-A Electric recording process of images using electron sensitive layer containing trivalent cobalt complex and compound having conjugated π bond system FUJI PHOTO FILM CO., LTD. (JP) 1978-12-26 US disclosed