SCHEMBL344146

SCHEMBL344146

COC1(C)C=CC(C(=O)c2ccccc2)C(O)=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 5/20 0.36
EPHX1 P07099 2/20 0.35
CES1 P23141 2/20 0.34
SRC P12931 1/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALDH1A1 P00352 3/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
PGR P06401 1/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.33
SLC6A2 P23975 1/20 0.33
PDE4A P27815 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
HRH1 P35367 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3120601 0.85 TSHR (0.36) HTTSMN1; SMN2TSHREPHX1CES1
SCHEMBL155031 0.84
SCHEMBL8172322 0.84 TSHR (0.35) HTTSMN1; SMN2TSHREPHX1CES1
SCHEMBL9732807 0.83 TSHR (0.34) HTTSMN1; SMN2TSHREPHX1CES1
SCHEMBL7855173 0.83 TSHR (0.34) HTTSMN1; SMN2TSHREPHX1CES1
SCHEMBL180232 0.83 TSHR (0.34) HTTSMN1; SMN2TSHREPHX1CES1
SCHEMBL10888869 0.82 MEN1 (0.39) HTTSMN1; SMN2TSHRKMT2AMEN1
SCHEMBL8166850 0.80 TSHR (0.32) HTTSMN1; SMN2TSHREPHX1CES1
SCHEMBL10823202 0.79 ALDH1A1 (0.33) HTTSMN1; SMN2TSHREPHX1CES1
SCHEMBL158108 0.78 HTT (0.36) HTTSMN1; SMN2TSHREPHX1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 553 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117597403-A Composition and method for protecting a coating from harmful effects of exposure to UV-C light 塞特工业公司 2024-02-23 CN claimed
CN-116783246-A Compositions and methods for protecting organic polymeric materials from discoloration due to exposure to UV-C light 塞特工业公司 2023-09-19 CN claimed
CN-116745353-A Compositions and methods for protecting organic polymeric materials from the deleterious effects of UV-C light exposure 塞特工业公司 2023-09-12 CN claimed
WO-2009080427-A1 METHOD FOR PRODUCING UV-ABSORBING HYBRID MATERIALS BASF SE (DE) 2009-07-02 WO claimed
EP-4289275-B1 INSECT REPELLENT COMPOSITION UNIV WIEN BODENKULTUR (AT) 2026-05-27 EP disclosed
US-20250359546-A1 NOVEL INSECT REPELLENT COMPOSITION UNIVERSITÄT FÜR BODENKULTUR WIEN (AT) 2025-11-27 US disclosed
EP-3663366-B1 USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS SYMRISE AG (DE) 2025-01-08 EP disclosed
CN-118338957-A Oil-in-water type composition 株式会社资生堂 2024-07-12 CN disclosed
CN-113164433-B Oily moisturizer and external composition for skin containing same 日清奥利友集团株式会社 2024-07-09 CN disclosed
CN-118255914-A Copolymer having carbosiloxane dendrimer structure, and composition, cosmetic raw material, film-forming agent and cosmetic containing the copolymer 陶氏东丽株式会社 2024-06-28 CN disclosed
US-20240207153-A1 DESFERRIOXAMINES AND COMPOSITION CONTAINING UV LIGHT PROTECTION FILTERS EVONIK DR. STRAETMANS GMBH (DE) 2024-06-27 US disclosed
CN-118234468-A Cosmetic product 株式会社资生堂 2024-06-21 CN disclosed
EP-0674505-A1 SYNERGISTIC COMBINATIONS OF ACTIVE SUBSTANCE FOR THE COSMETIC OR DERMATOLOGICAL CARE OF THE SKIN, HAIR AND NAILS Beiersdorf Aktiengesellschaft (DE) 1995-10-04 EP disclosed
WO-1995015147-A1 USE OF L-ARGININE, L-ORNITHINE OR L-CITRULLINE AND TOPICAL PREPARATIONS WITH THESE SUBSTANCES BEIERSDORF AG (DE) 1995-06-08 WO disclosed
WO-1994021241-A1 NEW USE OF ANTI-ACNE AGENTS BEIERSDORF AG (DE) 1994-09-29 WO disclosed
WO-1994021222-A1 SUNBLOCKING, EMULSIFYING PROTEINACEOUS PARTICULATE LOTION AND MANUFACTURE NURTURE, INC. (US) 1994-09-29 WO disclosed
WO-1994017780-A1 WATERPROOF COSMETIC OR DERMATOLOGICAL PHOTOPROTECTIVE PREPARATIONS BEIERSDORF AG (DE) 1994-08-18 WO disclosed
WO-1994014412-A1 SYNERGISTIC COMBINATIONS OF ACTIVE SUBSTANCE FOR THE COSMETIC OR DERMATOLOGICAL CARE OF THE SKIN, HAIR AND NAILS BEIERSDORF AG (DE) 1994-07-07 WO disclosed
EP-0190326-A1 WEATHERABLE ABRASION RESISTANT ETHERIFIED AMINOPLAST DERIVED COATING FOR PLASTIC SUBSTRATES GENERAL ELECTRIC COMPANY (US) 1986-08-13 EP disclosed
WO-1986001217-A1 WEATHERABLE ABRASION RESISTANT ETHERIFIED AMINOPLAST DERIVED COATING FOR PLASTIC SUBSTRATES GENERAL ELECTRIC COMPANY (US) 1986-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250359546-A1 NOVEL INSECT REPELLENT COMPOSITION EXOSC10, EPCAM, ICAM1 HTT 2220/4885SMN1; SMN2 4599/4885TSHR 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.