Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 16/20 | 0.65 |
| ▸ | FAAH | O00519 | 6/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12321793 | 0.82 | HSP90AA1 (0.84) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL95324 | 0.81 | MGLL (1.00) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL7772704 | 0.78 | MGLL (0.65) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL25584213 | 0.78 | MGLL (0.58) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL8467244 | 0.78 | MGLL (0.77) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL17231642 | 0.78 | MGLL (0.58) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL9720879 | 0.77 | MGLL (0.62) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL8505932 | 0.76 | SCN2A (0.63) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL28578280 | 0.75 | MGLL (0.60) | MGLLFAAHHSP90AA1TDP1PKM | |
| SCHEMBL571682 | 0.75 | HSP90AA1 (1.00) | MGLLFAAHHSP90AA1TDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928503-B1 | CONJUGATES OF AURISTATIN COMPOUNDS | MERSANA THERAPEUTICS INC (US) | 2019-02-20 | — | — | EP | disclosed |
| US-20150314008-A1 | AURISTATIN COMPOUNDS AND CONJUGATES THEREOF | MERSANA THERAPEUTICS, INC. | 2015-11-05 | — | — | US | disclosed |
| WO-2014093379-A1 | AURISTATIN COMPOUNDS AND CONJUGATES THEREOF | MERSANA THERAPEUTICS, INC. (US) | 2014-06-19 | — | — | WO | disclosed |
| CN-101508844-B | Resin composition, prepreg and their uses | MITSUBISHI GAS CHEMICAL CO | 2013-05-01 | — | — | CN | disclosed |
| CN-101508844-A | Resin composition, prepreg and their uses | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-08-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150314008-A1 | AURISTATIN COMPOUNDS AND CONJUGATES THEREOF | PBRM1, BRWD1, BRDT | MGLL 4358/4885FAAH 3977/4885HSP90AA1 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.