SCHEMBL571682

SCHEMBL571682

O=C1C=CC(=O)N1c1ccc(Nc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 4/20 1.00
MGLL Q99685 14/20 0.65
FAAH O00519 7/20 0.62
MAPK1 P28482 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
HSD17B10 Q99714 2/20 0.52
ALDH1A1 P00352 2/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
PTGS2 P35354 1/20 0.52
HTR2B P41595 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PKM P14618 2/20 0.50
DDAH1 O94760 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
MEN1 O00255 1/20 0.49
GFER P55789 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12321793 0.92 HSP90AA1 (0.84) HSP90AA1MGLLFAAHMAPK1TDP1
SCHEMBL29405415 0.83 HSP90AA1 (0.70) HSP90AA1MGLLFAAHMAPK1TDP1
SCHEMBL8467244 0.82 MGLL (0.77) HSP90AA1MGLLFAAHMAPK1TDP1
SCHEMBL9623110 0.81 HSP90AA1 (0.66) HSP90AA1ALDH1A1L3MBTL1PKMMEN1
SCHEMBL8920586 0.80 MGLL (1.00) HSP90AA1MGLLFAAHMAPK1TDP1
SCHEMBL18713 0.80 MGLL (1.00) HSP90AA1MGLLFAAHMAPK1TDP1
Benzene SCHEMBL28088808 0.80 MGLL (1.00) HSP90AA1MGLLFAAHMAPK1TDP1
SCHEMBL8965241 0.78 HSP90AA1 (0.65) HSP90AA1MAPK1TDP1HSD17B10ALDH1A1
SCHEMBL2132967 0.78 KMT2A (0.68) HSP90AA1MAPK1TDP1HSD17B10ALDH1A1
SCHEMBL15841338 0.78 MGLL (0.95) HSP90AA1MGLLFAAHMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 548 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421380-B2 Acrylic copolymer and rubber material OSAKA SODA CO., LTD. (JP) 2025-09-23 US claimed
CN-119060441-B Reinforced halogen-free flame-retardant cable and preparation method thereof 广东程通电线电缆厂有限公司 2025-06-13 CN claimed
CN-119798805-A Ageing-resistant rubber product and preparation method thereof 安徽省中能新材料有限公司 2025-04-11 CN claimed
CN-119241967-B Low-VOC (volatile organic compound) automobile sealing strip composite PVC (polyvinyl chloride) material and preparation method thereof 兴宇汽车零部件股份有限公司 2025-04-01 CN claimed
CN-119735992-A Bird damage prevention method and construction process thereof 内蒙古电力(集团)有限责任公司 2025-04-01 CN claimed
CN-119570342-A Method for preparing environment-friendly coating by using modified polyaspartic acid ester resin and isocyanate and application thereof 佛山市三水联美化工有限公司 2025-03-07 CN claimed
US-20250075019-A1 METHOD FOR MANUFACTURING NITRILE BUTADIENE RUBBER NANTEX INDUSTRY CO., LTD. (TW) 2025-03-06 US claimed
CN-118755187-B Crosslinked polyethylene insulated cable and preparation method thereof 淄博宇辰塑胶有限公司 2025-02-25 CN claimed
CN-118179281-B Preparation method of conductive carbon nanotube hollow fiber membrane resistant to membrane pollution and application of electrochemical coupling in water treatment 大连理工大学 2025-02-14 CN claimed
CN-119331201-A Preparation method of dispersing agent for inkjet 广东核心新材料股份有限公司 2025-01-21 CN claimed
CN-101250305-A High heat-resistant rubber composite material for conveyor belt covering UNIV BEIJING CHEMICAL (CN) 2008-08-27 CN claimed
US-20080029430-A1 Hydraulic Fluid Compositions and Preparation Thereof CHEVRON USA INC. (US) 2008-02-07 US claimed
WO-2007121039-A2 POLYMER AND LUBRICATING COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2007-10-25 WO claimed
US-20050153849-A1 Graft copolymers, method of making and compositions containing the same AFTON CHEMICAL CORPORATION 2005-07-14 US claimed
EP-1553115-A2 Graft copolymers, method of making and compositions containing the same Afton Chemical Corporation (US) 2005-07-13 EP claimed
EP-1000117-A1 RUBBER COMPOSITION FOR COLOUR TYRE Compagnie Générale des Etablissements MICHELIN-MICHELIN & CIE (FR) 2000-05-17 EP claimed
US-5936038-A MIXTURE CONTAINING ELASTOMER HAVING PENDANT REACTIVE AMINE GROUP AND PHENOLIC RESIN CURATIVE THE UNIVERSITY OF AKRON (US) 1999-08-10 US claimed
WO-1999006480-A1 RUBBER COMPOSITION FOR COLOUR TYRE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN-MICHELIN & CIE. (FR) 1999-02-11 WO claimed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US claimed
US-4376846-A OIL AND OZONE RESISTANT AND HEAT AGING RESISTANT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-03-15 US claimed