SCHEMBL8467244

SCHEMBL8467244

Cc1ccc(Nc2ccc(N3C(=O)C=CC3=O)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 0.77
HSP90AA1 P07900 4/20 0.70
FAAH O00519 4/20 0.58
F2 P00734 1/20 0.52
ELANE P08246 1/20 0.52
CTSG P08311 1/20 0.52
CMA1 P23946 1/20 0.52
CTRC Q99895 1/20 0.52
CCR6 P51684 1/20 0.48
PKM P14618 1/20 0.48
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HPGD P15428 1/20 0.47
APP P05067 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28521284 0.95 MGLL (0.69) MGLLHSP90AA1FAAHF2ELANE
SCHEMBL12321793 0.90 HSP90AA1 (0.84) MGLLHSP90AA1FAAHCCR6PKM
SCHEMBL140025 0.88 MGLL (1.00) MGLLHSP90AA1FAAHF2ELANE
SCHEMBL571682 0.82 HSP90AA1 (1.00) MGLLHSP90AA1FAAHPKMMAPK1
SCHEMBL9176987 0.82 MGLL (0.87) MGLLHSP90AA1FAAHF2ELANE
SCHEMBL8467655 0.80 HSP90AA1 (0.64) MGLLHSP90AA1FAAHPKMMAPK1
SCHEMBL8467713 0.80 MGLL (0.79) MGLLHSP90AA1FAAHELANECCR6
SCHEMBL15811642 0.78 MGLL (0.65) MGLLHSP90AA1FAAHCCR6PKM
SCHEMBL5068628 0.77 MGLL (0.77) MGLLHSP90AA1FAAHF2ELANE
SCHEMBL22862085 0.77 MGLL (0.77) MGLLHSP90AA1FAAHF2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5936038-A MIXTURE CONTAINING ELASTOMER HAVING PENDANT REACTIVE AMINE GROUP AND PHENOLIC RESIN CURATIVE THE UNIVERSITY OF AKRON (US) 1999-08-10 US claimed
US-4376846-A OIL AND OZONE RESISTANT AND HEAT AGING RESISTANT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-03-15 US claimed
WO-2022138729-A1 ACRYLIC COPOLYMER COMPOSITION AND CROSSLINKED PRODUCT OF SAME 株式会社大阪ソーダ 2022-06-30 WO disclosed
US-5936038-A MIXTURE CONTAINING ELASTOMER HAVING PENDANT REACTIVE AMINE GROUP AND PHENOLIC RESIN CURATIVE THE UNIVERSITY OF AKRON (US) 1999-08-10 US disclosed
EP-0570825-B1 Tire sidewall composition containing silica having low PH GOODYEAR TIRE & RUBBER (US) 1996-08-07 EP disclosed
EP-0475215-B1 Carboxylic acid esters with thio groups GOODYEAR TIRE & RUBBER (US) 1994-10-19 EP disclosed
EP-0570825-A1 Tire sidewall composition containing silica having low PH THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-11-24 EP disclosed
US-5244028-A Natural rubber or polybutadiene, silica, antidegradation agent, carbon black THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-09-14 US disclosed
US-5216049-A A phenolic or amine stabilizer and an organothioalkylene styrene bound to a polymer; aging resistance; rubbers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-06-01 US disclosed
EP-0475215-A1 Carboxylic acid esters with thio groups THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-18 EP disclosed
US-5069819-A SYNERGISTS FOR CONVENTIONAL PHENOLIC AND AMINE ANTIOXIDANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-12-03 US disclosed
US-4376846-A OIL AND OZONE RESISTANT AND HEAT AGING RESISTANT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-03-15 US disclosed