Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730698 | 0.81 | CA1 (0.57) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL8131 | 0.77 | CA1 (0.58) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL31501939 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL15372784 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL456018 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL31370732 | 0.77 | HTR2A (0.58) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL20362789 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL28050 | 0.77 | HTR2A (0.58) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL4992955 | 0.77 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL15497037 | 0.77 | CA1 (0.49) | CA1CA2HTR2AKMT2AFABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895502-B2 | β2-glycoprotein I peptide inhibitors | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130165391-A1 | B2-GLYCOPROTEIN I PEPTIDE INHIBITORS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-06-27 | — | — | US | disclosed |
| WO-2012030949-A2 | B2-GLYCOPROTEIN I PEPTIDE INHIBITORS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-03-08 | — | — | WO | disclosed |