SCHEMBL15817

SCHEMBL15817

Fc1ccc(OCc2ccccc2)cc1F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.61
LMNA P02545 1/20 0.55
CYP1A2 P05177 1/20 0.55
PTGS1 P23219 1/20 0.55
SLC6A2 P23975 1/20 0.55
CYP2C19 P33261 1/20 0.55
PTGS2 P35354 1/20 0.55
SLC6A3 Q01959 1/20 0.55
HIF1A Q16665 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
CTSV O60911 1/20 0.55
CTSL P07711 1/20 0.55
MAOB P27338 10/20 0.54
MAOA P21397 2/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TOP1 P11387 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31166954 0.85 ALOX5 (0.58) ALOX5LMNACYP1A2PTGS1SLC6A2
SCHEMBL12743254 0.84 MRGPRX4 (0.68) ALOX5LMNACYP1A2PTGS1SLC6A2
SCHEMBL8251097 0.84 MAOB (0.57) ALOX5LMNACYP1A2PTGS1SLC6A2
SCHEMBL29502845 0.84 MAOB (0.58) ALOX5LMNACYP1A2PTGS1SLC6A2
SCHEMBL7879365 0.84 ALOX5 (0.56) ALOX5LMNACYP1A2PTGS1SLC6A2
SCHEMBL10212718 0.84 ALOX5 (0.56) ALOX5LMNACYP1A2PTGS1SLC6A2
SCHEMBL2387082 0.84 MAOB (0.56) ALOX5LMNACYP1A2PTGS1SLC6A2
SCHEMBL7779413 0.84 LMNA (0.59) ALOX5LMNACYP1A2PTGS1SLC6A2
SCHEMBL16822445 0.84 ALOX5 (0.56) ALOX5LMNACYP1A2PTGS1SLC6A2
SCHEMBL30065009 0.84 MAOB (0.57) ALOX5LMNACYP1A2PTGS1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2609065-B1 PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE ALBEMARLE CORP (US) 2015-07-08 EP claimed
CN-103201244-B Processes for producing 1-bromo-2 (cyclopropyl methoxy)-5 fluoro-4- methoxybenzene ALBEMARLE CORP 2015-06-17 CN claimed
EP-2609065-A1 PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE Albemarle Corporation (US) 2013-07-03 EP claimed
US-20130109887-A1 PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE ALBERMARLE CORPORATION (US) 2013-05-02 US claimed
WO-2012027134-A1 PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE ALBEMARLE CORPORATION (US) 2012-03-01 WO claimed
CN-118056834-A Fused ring pyridone derivatives, preparation method and application thereof 合肥医工医药股份有限公司 2024-05-21 CN disclosed
WO-2024059041-A1 BENZO-FUSED N-HETEROCYCLES AND USES THEREOF KUMQUAT BIOSCIENCES, INC. (US) 2024-03-21 WO disclosed
EP-2609065-B1 PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE ALBEMARLE CORP (US) 2015-07-08 EP disclosed
EP-2609065-B1 PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE ALBEMARLE CORP (US) 2015-07-08 EP disclosed
CN-103201244-B Processes for producing 1-bromo-2 (cyclopropyl methoxy)-5 fluoro-4- methoxybenzene ALBEMARLE CORP 2015-06-17 CN disclosed
EP-2609065-A1 PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE Albemarle Corporation (US) 2013-07-03 EP disclosed
US-20130109887-A1 PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE ALBERMARLE CORPORATION (US) 2013-05-02 US disclosed
US-20130109887-A1 PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE ALBERMARLE CORPORATION (US) 2013-05-02 US disclosed
US-20130109887-A1 PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE ALBERMARLE CORPORATION (US) 2013-05-02 US disclosed
WO-2012027134-A1 PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE ALBEMARLE CORPORATION (US) 2012-03-01 WO disclosed
WO-2012027134-A1 PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE ALBEMARLE CORPORATION (US) 2012-03-01 WO disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130109887-A1 PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE CYP4B1, CYP4X1, CYP1B1 ALOX5 893/4885LMNA 3375/4885CYP1A2 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.