Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15365 | 0.88 | MAOB (0.58) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL27771711 | 0.88 | MAOB (0.58) | MAOBGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16034065 | 0.87 | ALOX5 (0.44) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28397428 | 0.86 | KAT6A (0.47) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28396058 | 0.86 | ALOX5 (0.47) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL15817 | 0.85 | ALOX5 (0.61) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL31464123 | 0.84 | ALOX5 (0.49) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL13412635 | 0.83 | ALOX5 (0.63) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28399722 | 0.82 | LMNA (0.52) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL29704022 | 0.81 | KDM1A (0.55) | MAOBRAB9ASMN1; SMN2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698520-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | Gandeeva Therapeutics, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220708-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | GANDEEVA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |