⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27431959 | 0.97 | P2RX7 (0.52) | — | |
| Bromide SCHEMBL10718877 | 0.97 | P2RX7 (0.52) | — | |
| Hydrochloric Acid SCHEMBL25337662 | 0.97 | P2RX7 (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL17104818 | 0.97 | P2RX7 (0.52) | — | |
| Hydrochloric Acid SCHEMBL27440453 | 0.97 | P2RX7 (0.52) | — | |
| Pyridine SCHEMBL1880098 | 0.88 | P2RX7 (0.45) | — | |
| Thiophene SCHEMBL357409 | 0.86 | P2RX7 (0.43) | — | |
| SCHEMBL28417574 | 0.86 | P2RX7 (0.43) | — | |
| Pyrrole SCHEMBL985895 | 0.86 | P2RX7 (0.48) | — | |
| Trifluoroacetic Acid SCHEMBL3996079 | 0.84 | L3MBTL1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1765 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734976-A2 | AGENTS FOR TREATING DISORDERS INVOLVING RYANODINE RECEPTORS | RyCarma Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | claimed |
| EP-4688157-A1 | 3H-PYRAZOLO[4.3:f] QUINOLINE-BASED COMPOUNDS AS STING ANTAGONISTS | Purdue Research Foundation (US) | 2026-02-11 | — | — | EP | claimed |
| EP-4301736-B1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2025-10-08 | — | — | EP | claimed |
| US-20250230154-A1 | COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF | UBIX THERAPEUTICS, INC. (KR) | 2025-07-17 | — | — | US | claimed |
| CN-119841853-A | Crystal form of pyrimidine carboxamide compound and preparation method thereof | 上海泓博尚奕药物技术有限公司 | 2025-04-18 | — | — | CN | claimed |
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | claimed |
| CN-119403798-A | Novel compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | 东亚ST 株式会社 | 2025-02-07 | — | — | CN | claimed |
| WO-2025006617-A2 | AGENTS FOR TREATING DISORDERS INVOLVING RYANODINE RECEPTORS | ARMGO PHARMA, INC. (US) | 2025-01-02 | — | — | WO | claimed |
| US-20240383863-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | INSTITUTE FOR BASIC SCIENCE (KR) | 2024-11-21 | — | — | US | claimed |
| CN-113382990-B | Substituted pyrrolidinamide III | 格吕伦塔尔有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-1407985-A | Heterocyclic dihydropyrimidines as potassium channel inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2003-04-02 | — | — | CN | claimed |
| CN-1403446-A | Catalytic synthesis process of methyl substituted pyrimidyl urea derivative | DALIAN CHEMICAL PHYSICS INST (CN) | 2003-03-19 | — | — | CN | claimed |
| WO-2002098989-A1 | DYE MIXTURES OF FIBER-REACTIVE AZODYES AND THE USE THEREOF | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-12-12 | — | — | WO | claimed |
| EP-0977600-A2 | CONTRAST AGENTS | NYCOMED IMAGING A/S (NO) | 2000-02-09 | — | — | EP | claimed |
| WO-1998047541-B1 | CONTRAST AGENTS | — | 1998-11-26 | — | — | WO | claimed |
| WO-1998047541-A1 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1998-10-29 | — | — | WO | claimed |
| EP-0341081-B1 | Novel amino acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-07-05 | — | — | EP | claimed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | claimed |
| CN-1014990-B | Process for the preparation of 5-pyrimidinecarboxamides derivatives | UNIROYAL CHEM CO INC (US) | 1991-12-04 | — | — | CN | claimed |
| CN-86102767-A | The preparation method of 5-pyrimidine carboxamide analog derivative | — | 1987-01-07 | — | — | CN | claimed |