Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15643340 | 0.82 | ALDH1A1 (0.42) | MAPTALDH1A1NPC1CYP1A2CYP3A4 | |
| SCHEMBL15643545 | 0.80 | CYP19A1 (0.44) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14333772 | 0.79 | SMN1; SMN2 (0.53) | MAPTALDH1A1CYP1A2HTTLMNA | |
| SCHEMBL3253962 | 0.78 | GAA (0.44) | ALDH1A1POLBGAAHTTLMNA | |
| SCHEMBL15841258 | 0.78 | CYP19A1 (0.50) | MAPTALDH1A1NPC1CYP1A2CYP3A4 | |
| SCHEMBL12919527 | 0.77 | NPC1 (0.48) | MAPTALDH1A1NPC1CYP1A2CYP3A4 | |
| SCHEMBL4508326 | 0.77 | CYP19A1 (0.50) | ALDH1A1CYP19A1HTTSMN1; SMN2 | |
| SCHEMBL14992892 | 0.77 | SMN1; SMN2 (0.47) | MAPTALDH1A1HTTLMNAADAMTS4 | |
| SCHEMBL14334759 | 0.77 | AR (0.53) | ALDH1A1CYP19A1GAAHTTADAMTS4 | |
| SCHEMBL4515544 | 0.75 | CYP19A1 (0.46) | MAPTALDH1A1NPC1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014099837-A1 | SULFONAMIDE ANTHELMINTICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-06-26 | — | — | WO | claimed |
| WO-2014099837-A1 | SULFONAMIDE ANTHELMINTICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-06-26 | — | — | WO | disclosed |