SCHEMBL1581968

SCHEMBL1581968

c1c[nH]c(-n2cccn2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.42
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 3/20 0.39
LMNA P02545 3/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
G6PD P11413 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPK1 P28482 3/20 0.39
NPC1 O15118 1/20 0.39
F2RL1 P55085 3/20 0.38
KDM4A O75164 1/20 0.37
KDM4B O94953 1/20 0.37
KDM5C P41229 1/20 0.37
KDM5B Q9UGL1 1/20 0.37
GRM5 P41594 1/20 0.36
HTT P42858 3/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30099785 0.73 MAPK1 (0.46) NOTUMALDH1A1KDM4ELMNAMAPT
SCHEMBL13810752 0.68 ERCC1 (0.53) NOTUMALDH1A1KDM4ELMNAMAPK1
SCHEMBL4341894 0.67 NOTUM (0.78) NOTUMALDH1A1KDM4ELMNAMAPT
SCHEMBL308284 0.67 F2RL1 (0.41) NOTUMALDH1A1KDM4ELMNAMAPT
SCHEMBL4341886 0.66 MAPK1 (0.67) NOTUMALDH1A1KDM4ELMNAMAPT
SCHEMBL7972 0.66 MEN1 (0.31) ALDH1A1KDM4EMAPTMEN1GAA
SCHEMBL7902 0.65 ALDH1A1 (0.47) NOTUMALDH1A1KDM4ELMNAMAPT
SCHEMBL28039329 0.65 NOTUM (0.48) NOTUMALDH1A1KDM4ELMNAMAPT
SCHEMBL27607780 0.65 CYP3A4 (0.48) NOTUMALDH1A1LMNAMAPTMEN1
SCHEMBL28065853 0.65 NOTUM (0.50) NOTUMALDH1A1KDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104974091-B Diaryl pyrazole azole compound of 3 methyl 1,5 and its production and use 沈阳药科大学 2018-01-02 CN claimed
CN-107501181-A Protonate alkylated pyrazole azole ionic liquid and the method using its catalytically synthesizing cyclic carbonate ester 河南大学 2017-12-22 CN claimed
CN-104844514-B Diaryl pyrazole azole compound and preparation method and application 山东大学 2017-11-10 CN claimed
CN-103183640-B Diaryl pyrazole azole compounds and preparation method thereof and purposes SHENYANG PHARMACEUTICAL UNIVERSITY (CN) 2016-04-27 CN claimed
CN-104844514-A Diarylpyrazole compound as well as preparation method and application thereof UNIV SHANDONG 2015-08-19 CN claimed
CN-103183640-A Diaryl pyrazole compound, and preparation method and purpose thereof UNIV SHENYANG PHARMACEUTICAL 2013-07-03 CN claimed
CN-101979396-A Method for synthesizing sucrose-6-ester and sucralose NANJING GANBEIJIA BIOLOG TECHNOLOGY CO LTD 2011-02-23 CN claimed
EP-1740662-B1 INK JET INK SET EASTMAN KODAK CO (US) 2007-09-12 EP claimed
EP-1819721-A1 MICROCIN B17 ANALOGS AND METHODS FOR THEIR PREPARATION AND USE Plant Bioscience Limited (GB) 2007-08-22 EP claimed
EP-1740662-A1 INK JET INK SET EASTMAN KODAK COMPANY (US) 2007-01-10 EP claimed
US-20050229810-A1 Ink jet ink set EASTMAN KODAK COMPANY 2005-10-20 US claimed
EP-0573956-B1 Processing method using a color developer FUJI PHOTO FILM CO LTD (JP) 1998-09-02 EP claimed
EP-0362794-B1 Method for processing a silver halide photosensitive material for color photography FUJI PHOTO FILM CO LTD (JP) 1995-09-13 EP claimed
EP-0554756-B1 Color photographic recording material AGFA GEVAERT AG (DE) 1995-03-01 EP claimed
US-5342746-A Pyrazolo-azole couplers with coupler solvent of long chain unsaturated alcohol EASTMAN KODAK COMPANY (US) 1994-08-30 US claimed
EP-0255726-B1 METHOD FOR PROCESSING A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1992-01-15 EP claimed
US-4981773-A Method for stabilization of organic base substances against light FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US claimed
US-4965175-A CONTINUOUS PROCESSING OF CHLORIDE-RICH EMULSION, REDUCING BATH OPENING RATIO FOR DEVELOPER, OXIDATION RESISTANT PRESERVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1990-10-23 US claimed
EP-0362794-A2 Method for processing a silver halide photosensitive material for color photography FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP claimed
EP-0177765-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1990-03-14 EP claimed