Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL15820391 | 0.98 | BBOX1 (0.41) | BBOX1DNM1PSMD14PLA2G1BMMP2 | |
| Acetic Acid SCHEMBL15826260 | 0.91 | BBOX1 (0.42) | BBOX1PSMD14PLA2G1BMMP2RAD52 | |
| Acetic Acid SCHEMBL28437505 | 0.88 | DNM1 (0.53) | BBOX1DNM1PSMD14PLA2G1BMMP2 | |
| Acetic Acid SCHEMBL28670247 | 0.88 | DNM1 (0.53) | BBOX1DNM1PSMD14PLA2G1BMMP2 | |
| Acetic Acid SCHEMBL4634983 | 0.87 | CA1 (0.44) | BBOX1PSMD14PLA2G1BMMP2RAD52 | |
| Acetic Acid SCHEMBL28851660 | 0.86 | BBOX1 (0.57) | BBOX1DNM1PSMD14PLA2G1BMMP2 | |
| Hydrochloric Acid SCHEMBL15820823 | 0.84 | CYP3A4 (0.46) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Bromide SCHEMBL15820235 | 0.84 | DNM1 (0.48) | DNM1PSMD14PLA2G1BMMP2RAD52 | |
| Acetic Acid SCHEMBL29126254 | 0.84 | DNM1 (0.48) | BBOX1DNM1PSMD14PLA2G1BMMP2 | |
| Bromide SCHEMBL15822036 | 0.82 | MEN1 (0.48) | DNM1PSMD14PLA2G1BMMP2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150335547-A1 | ORAL CARE COMPOSITION CONTAINING IONIC LIQUIDS | COLGATE-PALMOLIVE COMPANY (US) | 2015-11-26 | — | — | US | disclosed |
| EP-2934469-A2 | ORAL CARE COMPOSITION CONTAINING IONIC LIQUIDS | Colgate-Palmolive Company (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014098871-A2 | ORAL CARE COMPOSITION CONTAINING IONIC LIQUIDS | COLGATE-PALMOLIVE COMPANY (US) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335547-A1 | ORAL CARE COMPOSITION CONTAINING IONIC LIQUIDS | MCOLN3, TAS2R39, TAS2R40 | BBOX1 4846/4885DNM1 1540/4885PSMD14 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.