Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307480 | 0.88 | SKP2 (0.44) | HTR1DHTR1BNOS2ALDH1A1HPGD | |
| SCHEMBL24753019 | 0.85 | ALDH1A1 (0.34) | HTR1DHTR1BNOS2ALDH1A1HPGD | |
| SCHEMBL3677675 | 0.84 | CCR5 (0.42) | ALDH1A1HPGDSKP2 | |
| SCHEMBL324195 | 0.79 | HRH3 (0.48) | HTR1DHTR1BNOS2ALDH1A1HPGD | |
| SCHEMBL12305002 | 0.79 | HTR1D (0.41) | HTR1DHTR1BNOS2ALDH1A1HPGD | |
| SCHEMBL3859523 | 0.78 | HTR1D (0.38) | HTR1DHTR1BALDH1A1HPGDKDM4E | |
| SCHEMBL8471196 | 0.76 | EDNRB (0.33) | HTR1DHTR1BALDH1A1HPGDKDM4E | |
| SCHEMBL22080839 | 0.75 | LDHA (0.38) | HTR1DNOS2ALDH1A1LDHALDHB | |
| SCHEMBL18704816 | 0.75 | CYP3A4 (0.44) | HTR1DNOS2ALDH1A1HPGDLDHA | |
| SCHEMBL13361284 | 0.75 | HTR1D (0.36) | HTR1DHTR1BALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935230-A2 | HERBICIDALLY ACTIVE CYCLIC DIONE COMPOUNDS, OR DERIVATIVES THEREOF, SUBSTITUTED BY A PHENYL WHICH HAS AN ALKYNYL-CONTAINING SUBSTITUENT | Syngenta Limited (GB) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014096289-A2 | HERBICIDALLY ACTIVE CYCLIC DIONE COMPOUNDS, OR DERIVATIVES THEREOF, SUBSTITUTED BY A PHENYL WHICH HAS AN ALKYNYL-CONTAINING SUBSTITUENT | SYNGENTA LIMITED (GB) | 2014-06-26 | — | — | WO | disclosed |