Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834530 | 0.94 | PDGFRB (0.47) | POLBHTTCHEK1GAACYP3A4 | |
| SCHEMBL15809180 | 0.85 | MAPT (0.42) | POLBHTTCHEK1CYP3A4L3MBTL1 | |
| SCHEMBL15827615 | 0.83 | GAA (0.45) | HTTGAAPDGFRBFGFR1PDGFRA | |
| SCHEMBL28604145 | 0.83 | HTT (0.47) | POLBHTTCHEK1GAACYP3A4 | |
| SCHEMBL12190692 | 0.83 | PDGFRB (0.51) | POLBHTTCHEK1GAACYP3A4 | |
| SCHEMBL8902175 | 0.83 | CHEK1 (0.51) | POLBHTTCHEK1GAACYP3A4 | |
| SCHEMBL2899450 | 0.83 | POLB (0.52) | POLBHTTCHEK1GAACYP3A4 | |
| SCHEMBL9793659 | 0.82 | GAA (0.55) | POLBHTTCHEK1GAACYP3A4 | |
| SCHEMBL29160276 | 0.82 | L3MBTL1 (0.47) | POLBHTTCHEK1GAACYP3A4 | |
| SCHEMBL17137155 | 0.82 | POLB (0.49) | POLBHTTCYP3A4L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2746250-B1 | Precursors and process for the production of 18F-labelled amino acids | ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) | 2017-09-27 | — | — | EP | disclosed |
| WO-2014095739-A1 | PRECURSORS AND PROCESS FOR THE PRODUCTION OF 18F-LABELLED AMINO ACIDS | ABX ADVANCED BIOCHEMICAL COMPOUNDS (DE) | 2014-06-26 | — | — | WO | disclosed |
| EP-2746250-A1 | Precursors and process for the production of 18F-labelled amino acids | ABX Advanced Biochemical Compounds GmbH (DE) | 2014-06-25 | — | — | EP | disclosed |