Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 9/20 | 0.53 |
| ▸ | INSR | P06213 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.50 |
| ▸ | ITGAM | P11215 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14860726 | 1.00 | MAP3K5 (0.53) | MAP3K5INSRIGF1RITGB2ITGAM | |
| SCHEMBL14860725 | 1.00 | MAP3K5 (0.53) | MAP3K5INSRIGF1RITGB2ITGAM | |
| SCHEMBL14860691 | 0.88 | CFTR (0.55) | MAP3K5INSRIGF1RITGB2ITGAM | |
| SCHEMBL21634346 | 0.88 | CFTR (0.55) | MAP3K5INSRIGF1RITGB2ITGAM | |
| SCHEMBL15827152 | 0.88 | CFTR (0.55) | MAP3K5INSRIGF1RITGB2ITGAM | |
| SCHEMBL14860690 | 0.88 | CFTR (0.55) | MAP3K5INSRIGF1RITGB2ITGAM | |
| SCHEMBL3895153 | 0.84 | MEN1 (0.54) | MAP3K5INSRIGF1RITGB2ITGAM | |
| SCHEMBL3895157 | 0.84 | MEN1 (0.54) | MAP3K5INSRIGF1RITGB2ITGAM | |
| SCHEMBL15827150 | 0.83 | MAP3K5 (0.56) | MAP3K5INSRIGF1RMAPTMEN1 | |
| SCHEMBL14860667 | 0.83 | MAP3K5 (0.56) | MAP3K5INSRIGF1RMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228548-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | AVIXGEN INC. (KR) | 2021-07-29 | — | — | US | disclosed |
| EP-3827827-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | Avixgen Inc. (KR) | 2021-06-02 | — | — | EP | disclosed |
| US-8759536-B2 | Rhodanine derivatives, method for preparing same, and pharmaceutical composition for the prevention or treatment of aids containing the rhodanine derivatives as active ingredients | AVIXGEN INC. (KR) | 2014-06-24 | — | — | US | disclosed |
| US-8759536-B2 | Rhodanine derivatives, method for preparing same, and pharmaceutical composition for the prevention or treatment of aids containing the rhodanine derivatives as active ingredients | AVIXGEN INC. (KR) | 2014-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210228548-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | COL2A1, COL1A1, SYVN1 | MAP3K5 3896/4885INSR 4549/4885IGF1R 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.