SCHEMBL15827481

SCHEMBL15827481

CSC(=O)Nc1ccc(Cc2ccc(N3C(=O)N(c4ccc(Cc5ccc(NC(=O)SC)cc5)cc4)C3=O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 1/20 0.42
▸ MGLL Q99685 1/20 0.42
▸ SAE1 Q9UBE0 3/20 0.42
▸ UBA2 Q9UBT2 3/20 0.42
▸ TSHR P16473 1/20 0.42
▸ LMNA P02545 2/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ POLB P06746 1/20 0.41
▸ SCN2A Q99250 1/20 0.40
▸ F2 P00734 1/20 0.38
▸ ELANE P08246 1/20 0.38
▸ CTSG P08311 1/20 0.38
▸ CMA1 P23946 1/20 0.38
▸ CTRC Q99895 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ MAPT P10636 2/20 0.37
▸ HPGD P15428 2/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ CCNC P24863 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15981315 0.93 SAE1 (0.39) FAAHMGLLSAE1UBA2TSHR
SCHEMBL11699518 0.85 SAE1 (0.53) SAE1UBA2TSHRLMNAMEN1
SCHEMBL15827488 0.83 MAPK14 (0.36) FAAHMGLLSAE1UBA2TSHR
SCHEMBL15981314 0.79 POLB (0.53) SAE1UBA2TSHRLMNAMEN1
SCHEMBL15827487 0.79 MAPT (0.33) FAAHMGLLSAE1UBA2TSHR
SCHEMBL15985322 0.75 MAPK14 (0.35) FAAHMGLLSAE1UBA2TSHR
SCHEMBL10438301 0.73 MGLL (0.64) FAAHMGLLTSHRLMNAMEN1
SCHEMBL12049311 0.72 PLG (0.49) TP53
Hydrochloric Acid SCHEMBL4888001 0.70 PLG (0.50) —
SCHEMBL18854171 0.70 L3MBTL1 (0.54) SAE1UBA2TSHRLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2746823-B1 URETHANE-BASED OPTICAL COMPONENT AND MANUFACTURING PROCESS THEREFOR HOYA CORP (JP) 2016-05-04 — — EP disclosed
US-9193831-B2 Urethane-based optical component and manufacturing process therefor HOYA CORPORATION (JP) 2015-11-24 — — US disclosed
US-20140243496-A1 URETHANE-BASED OPTICAL COMPONENT AND MANUFACTURING PROCESS THEREFOR HOYA CORPORATION (JP) 2014-08-28 — — US disclosed
EP-2746823-A1 URETHANE-BASED OPTICAL COMPONENT AND MANUFACTURING PROCESS THEREFOR Hoya Corporation (JP) 2014-06-25 — — EP disclosed
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