Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15985322 | 0.85 | MAPK14 (0.35) | MAPK14SAE1UBA2TSHRTP53 | |
| SCHEMBL15985321 | 0.83 | NPC1 (0.44) | SAE1UBA2TSHRTP53MEN1 | |
| SCHEMBL15827481 | 0.83 | FAAH (0.42) | MAPK14SAE1UBA2TSHRTP53 | |
| SCHEMBL15985169 | 0.82 | TP53 (0.31) | MAPK14TP53MAPTMEN1KMT2A | |
| SCHEMBL16638893 | 0.80 | SAE1 (0.47) | MAPK14SAE1UBA2TSHRMAPT | |
| SCHEMBL15981315 | 0.76 | SAE1 (0.39) | MAPK14SAE1UBA2TSHRFAAH | |
| SCHEMBL16638889 | 0.75 | SAE1 (0.42) | MAPK14SAE1UBA2MAPTMEN1 | |
| SCHEMBL15827487 | 0.74 | MAPT (0.33) | SAE1UBA2TSHRTP53FAAH | |
| SCHEMBL11699518 | 0.68 | SAE1 (0.53) | SAE1UBA2TSHRMAPTMEN1 | |
| SCHEMBL10438301 | 0.66 | MGLL (0.64) | TSHRFAAHMGLLMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2746823-B1 | URETHANE-BASED OPTICAL COMPONENT AND MANUFACTURING PROCESS THEREFOR | HOYA CORP (JP) | 2016-05-04 | — | — | EP | disclosed |
| EP-2746823-A1 | URETHANE-BASED OPTICAL COMPONENT AND MANUFACTURING PROCESS THEREFOR | Hoya Corporation (JP) | 2014-06-25 | — | — | EP | disclosed |