Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672462 | 0.80 | PDE4B (0.34) | ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL1825035 | 0.76 | PDCD1 (0.33) | NPC1RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL14645960 | 0.76 | PDE4B (0.34) | ALDH1A1CYP3A4 | |
| SCHEMBL15931779 | 0.72 | — | — | |
| SCHEMBL15893457 | 0.72 | — | — | |
| SCHEMBL15827464 | 0.72 | HPGD (0.36) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL1453850 | 0.72 | BRD4 (0.36) | FABP4NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6781256 | 0.71 | BRD4 (0.33) | — | |
| SCHEMBL1825938 | 0.69 | CYP2A6 (0.36) | RAB9AMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1820218 | 0.69 | MAPK1 (0.35) | NPC1MAPTALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2746289-A1 | Catalysts | Borealis AG (AT) | 2014-06-25 | — | — | EP | disclosed |