Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 2/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453850 | 0.86 | BRD4 (0.36) | BRD4BRD2PTGS1PTGS2TDO2 | |
| SCHEMBL61908 | 0.84 | PDCD1 (0.34) | BRD4AKT2AKT1 | |
| SCHEMBL29366427 | 0.84 | PDCD1 (0.34) | BRD4AKT2AKT1 | |
| Hydrochloric Acid SCHEMBL3822639 | 0.82 | ADRA2A (0.34) | BRD4TDO2AKT2AKT1 | |
| Dimethylamine SCHEMBL1453283 | 0.81 | TDO2 (0.33) | TDO2 | |
| SCHEMBL6056122 | 0.78 | PDCD1 (0.30) | — | |
| SCHEMBL1452295 | 0.78 | PDCD1 (0.30) | — | |
| SCHEMBL16683341 | 0.78 | PDCD1 (0.30) | — | |
| SCHEMBL1452790 | 0.77 | MAPK1 (0.39) | — | |
| SCHEMBL5838399 | 0.77 | PDK2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730756-B1 | HETEROGENEOUS TRANSITION METAL CATALYST WITH METALLOCENE IMPREGNATED | BOREALIS A/S (DK) | 2004-05-04 | — | — | US | disclosed |