Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | GLA | P06280 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TNKS2 | Q9H2K2 | 9/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307979 | 0.84 | KDM4E (0.59) | KDM4EGLAGAAHPGDALDH1A1 | |
| SCHEMBL9273141 | 0.79 | HPGD (0.63) | KDM4EHPGDALDH1A1SMN1; SMN2TNKS2 | |
| SCHEMBL592109 | 0.77 | KDM4E (1.00) | KDM4EGLAGAAHPGDALDH1A1 | |
| SCHEMBL29532206 | 0.77 | KDM4E (1.00) | KDM4EGLAGAAHPGDALDH1A1 | |
| SCHEMBL2795205 | 0.76 | KDM4E (0.67) | KDM4EGLAGAAHPGDALDH1A1 | |
| SCHEMBL15840846 | 0.75 | ATM (0.47) | MAOADYRK1APARP1HSD17B10 | |
| SCHEMBL1378769 | 0.73 | TNKS2 (0.75) | KDM4EGLAGAAHPGDALDH1A1 | |
| SCHEMBL13264599 | 0.73 | KDM4E (0.62) | KDM4EGLAGAAHPGDALDH1A1 | |
| SCHEMBL141348 | 0.73 | TNKS2 (0.66) | KDM4EGLAGAAHPGDALDH1A1 | |
| SCHEMBL2798886 | 0.73 | KDM4E (0.62) | KDM4EGLAGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458499-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-20160083782-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-03-24 | — | — | US | disclosed |
| US-9206474-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-20140178882-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORPORATION (US) | 2014-06-26 | — | — | US | disclosed |