SCHEMBL1582887

SCHEMBL1582887

CCC1=Cc2c(cccc2-c2cc3ccccc3c3ccccc23)C1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 3/20 0.38
HPGD P15428 2/20 0.38
HIF1A Q16665 2/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HTR2A P28223 1/20 0.33
NISCH Q9Y2I1 1/20 0.33
PNMT P11086 1/20 0.32
HTR7 P34969 2/20 0.32
HTR1A P08908 1/20 0.32
HTR6 P50406 1/20 0.32
CYP11B1 P15538 1/20 0.31
TRPM4 Q8TD43 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1582877 0.89 ALDH1A1 (0.36) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL1583323 0.87 HTR7 (0.40) ALDH1A1NISCHPNMTHTR7HTR1A
SCHEMBL22685830 0.82 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL1583270 0.76 DPP4 (0.39) PNMTHTR7HTR1A
SCHEMBL1583093 0.76 HTR7 (0.41) ALDH1A1HSD17B10HPGDTSHRCASP1
SCHEMBL7054232 0.74 KDM4E (0.45) ALDH1A1HSD17B10HIF1ATSHRHTR2A
SCHEMBL2970349 0.72 HTR6 (0.33) ALDH1A1HTR2AHTR6
SCHEMBL1582924 0.72 HTR7 (0.36) NISCHHTR7HTR1ACYP1A2
SCHEMBL7651334 0.71 HPRT1 (0.44) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL27483369 0.70 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDHIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773287-B2 Method for forming coating TOKYO OHKA KOGYO CO., LTD. (JP) 2023-10-03 US disclosed
US-20200369914-A1 METHOD FOR FORMING COATING TOKYO OHKA KOGYO CO., LTD. (JP) 2020-11-26 US disclosed
EP-1070729-B1 Transition metal compound, olefin polymerization catalyst component comprising said compound, olefin polymerization catalyst containing said component, process for olefin polymerization using said catalyst, propylene homopolymer, propylene copolymer and propylene elastomer MITSUI CHEMICALS INC (JP) 2011-09-28 EP disclosed
EP-0812854-B2 Novel transition metal compound, olefin polymerization catalyst comprising said compound, process for olefin polymerization using said catalyst and propylene homo- and copolymer MITSUI CHEMICALS INC (JP) 2011-04-20 EP disclosed
CN-1166702-C Propylene Homopolymer, Propylene Copolymer and Propylene Elastomer 三井化学株式会社 2004-09-15 CN disclosed
EP-0812854-B1 Novel transition metal compound, olefin polymerization catalyst comprising said compound, process for olefin polymerization using said catalyst and propylene homo- and copolymer MITSUI CHEMICALS INC (JP) 2001-08-16 EP disclosed
EP-1070729-A2 Transition metal compound, olefin polymerization catalyst component comprising said compound, olefin polymerization catalyst containing said component, process for olefin polymerization using said catalyst, propylene homopolymer, propylene copolymer and propylene elastomer Mitsui Chemicals, Inc. (JP) 2001-01-24 EP disclosed
CN-1249312-A Propylene Homopolymer, Propylene Copolymer and Propylene Elastomer MITSUI CHEMICALS INC (JP) 2000-04-05 CN disclosed
CN-1048501-C Transition metal compound, olefin polymerization catalyst, and olefin polymerization method MITSUI PETROCHEMICAL IND (JP) 2000-01-19 CN disclosed
US-5936053-A RIGIDITY, HEAT RESISTANCE, IMPACT STRENGTH; LOW PROPORTION OF INVERSELY INSERTED PROPYLENE UNITS MITSUI CHEMICALS, INC. (JP) 1999-08-10 US disclosed
US-5723640-A Transition metal compound having indenyl-containing metallocene MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-03 US disclosed
US-5710223-A COORDINATION POLYMERIZATION CATALYSTS FOR PROPYLENE HOMOPOLYMERS AND COPOLYMERS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1998-01-20 US disclosed
US-5705584-A COORDINATION CATALYSTS FOR ADDITION POLYMERIZATION OF PROPYLENE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-01-06 US disclosed
EP-0812854-A2 Novel transition metal compound, olefin polymerization catalyst comprising said compound, process for olefin polymerization using said catalyst and propylene homo- and copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-12-17 EP disclosed
US-5658997-A USING ZIRCONIUM COMPOUND WITH ALUMINOXANE AND ORGANOALUMINUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-08-19 US disclosed
US-5629254-A Substituted indenyl ring containing metallocene catalyst for propylene polymerization process MITSUI PETROCHEMICAL INDUSTRIES CO., LTD. (JP) 1997-05-13 US disclosed
CN-1103405-A Transition metal compound, olefin polymerization catalyst, olefin polymerization process, and propylene polymer MITSUI PETROCHEMICAL IND (JP) 1995-06-07 CN disclosed
EP-0629632-A2 Novel transition metal compound for use as a polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-12-21 EP disclosed