Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414489 | 0.89 | MAPK1 (0.55) | MAPK1SMN1; SMN2TSHRKDM4EHTT | |
| SCHEMBL2558799 | 0.85 | AR (0.51) | FFAR4TSHRKDM4EHTTLMNA | |
| SCHEMBL15831825 | 0.84 | FFAR4 (0.48) | FFAR4SMN1; SMN2TSHRKDM4EHTT | |
| SCHEMBL15831832 | 0.83 | FFAR4 (0.50) | FFAR4TSHRKDM4EHTTLMNA | |
| SCHEMBL15831819 | 0.83 | FFAR4 (0.50) | FFAR4TSHRKDM4EHTTLMNA | |
| SCHEMBL15831794 | 0.83 | FFAR4 (0.50) | FFAR4TSHRKDM4EHTTLMNA | |
| SCHEMBL17871933 | 0.82 | KDM4E (0.56) | FFAR4SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL15831831 | 0.81 | FFAR4 (0.49) | FFAR4SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL30918449 | 0.81 | HTR1A (0.51) | FFAR4ALDH1A1 | |
| SCHEMBL5345746 | 0.81 | HTR1A (0.51) | FFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072460-B | Morpholine derivative oxidation ring-opening method and product thereof | 西南大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113072460-A | Morpholine derivative oxidation ring-opening method and product thereof | 西南大学 | 2021-07-06 | — | — | CN | disclosed |
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | GRUENENTHAL GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | TRPV1, TRPV5, TRPV2 | MAPK1 4145/4885FFAR4 100/4885SMN1; SMN2 4541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.