Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.60 |
| ▸ | PPIB | P23284 | 1/20 | 0.60 |
| ▸ | PPIA | P62937 | 1/20 | 0.60 |
| ▸ | PPIG | Q13427 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2041329 | 0.87 | PPID (0.57) | PPIDPPIBPPIAPPIGHTT | |
| SCHEMBL7307996 | 0.85 | PPID (0.44) | PPIDPPIBPPIAPPIGHTT | |
| SCHEMBL15832194 | 0.81 | PPID (0.59) | PPIDPPIBPPIAPPIGHTT | |
| SCHEMBL9752201 | 0.77 | CYP4F2 (0.49) | HTTALDH1A1KDM4ENLRP3HSD17B10 | |
| Methylamine SCHEMBL8528191 | 0.77 | PPID (0.91) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL20957060 | 0.77 | CYP1A2 (0.47) | HTTALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL2036271 | 0.76 | PPID (0.71) | PPIDPPIBPPIAPPIGHTT | |
| SCHEMBL2037954 | 0.76 | PPID (0.71) | PPIDPPIBPPIAPPIGHTT | |
| SCHEMBL2044119 | 0.75 | PPID (1.00) | PPIDPPIBPPIAPPIGHTT | |
| SCHEMBL12643825 | 0.75 | PPID (1.00) | PPIDPPIBPPIAPPIGHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | FKBP3, FKBP4, FKBP5 | PPID 73/4885PPIB 51/4885PPIA 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.