Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14617672 | 0.87 | SMN1; SMN2 (0.70) | SMN1; SMN2EPHX1NPC1RAB9AMEN1 | |
| SCHEMBL20649314 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2EPHX1NPC1RAB9AMEN1 | |
| SCHEMBL13049648 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2EPHX1NPC1RAB9AMEN1 | |
| SCHEMBL17117240 | 0.80 | EPHX2 (0.82) | SMN1; SMN2EPHX1NPC1RAB9AMEN1 | |
| SCHEMBL14617667 | 0.79 | SMN1; SMN2 (0.81) | SMN1; SMN2EPHX1NPC1RAB9AMEN1 | |
| SCHEMBL3418508 | 0.79 | EPHX1 (1.00) | SMN1; SMN2EPHX1NPC1RAB9AMEN1 | |
| SCHEMBL15832155 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AMEN1HPGD | |
| SCHEMBL17117302 | 0.76 | CYP2C9 (0.74) | SMN1; SMN2EPHX1NPC1RAB9AKMT2A | |
| SCHEMBL16270338 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2EPHX1NPC1RAB9AMEN1 | |
| SCHEMBL25003647 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2EPHX1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-06-26 | — | — | US | disclosed |
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | FKBP3, FKBP4, FKBP5 | SMN1; SMN2 2177/4885EPHX1 645/4885NPC1 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.