Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15832193 | 0.81 | ALDH1A1 (0.48) | PPIDALDH1A1GAASMN1; SMN2CYP2D6 | |
| SCHEMBL12643847 | 0.77 | PPID (0.63) | PPIDGAASMN1; SMN2NAMPTMEN1 | |
| SCHEMBL15832176 | 0.74 | EPHX1 (0.46) | PPIDSMN1; SMN2NAMPTPOLBEPHX1 | |
| SCHEMBL14618806 | 0.73 | CYP1A2 (0.50) | ALDH1A1MEN1POLBKMT2ACYP1A2 | |
| SCHEMBL3577555 | 0.72 | DPP7 (0.70) | PPIDALDH1A1DPP7SIGMAR1KMT2A | |
| SCHEMBL15109520 | 0.69 | HRH3 (0.55) | ALDH1A1GAASMN1; SMN2SIGMAR1MEN1 | |
| SCHEMBL3401326 | 0.68 | CYP1A2 (0.74) | ALDH1A1MEN1POLBKMT2ACYP1A2 | |
| SCHEMBL15109525 | 0.68 | GAA (0.54) | ALDH1A1GAASMN1; SMN2SIGMAR1MEN1 | |
| SCHEMBL15832187 | 0.68 | PPID (0.42) | PPIDALDH1A1GAASMN1; SMN2EPHX1 | |
| SCHEMBL3408343 | 0.66 | ALDH1A1 (0.71) | ALDH1A1MEN1POLBKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | FKBP3, FKBP4, FKBP5 | PPID 73/4885ALDH1A1 3684/4885DPP7 3276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.