Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16351356 | 0.98 | PAX8 (0.38) | PAX8TSHRMEN1USP2POLB | |
| SCHEMBL16015594 | 0.96 | TSHR (0.38) | PAX8TSHRMEN1USP2POLB | |
| SCHEMBL15833423 | 0.95 | MEN1 (0.37) | PAX8TSHRMEN1USP2POLB | |
| SCHEMBL15833440 | 0.94 | PTPN1 (0.36) | MEN1USP2POLBKMT2APTPN1 | |
| SCHEMBL19767534 | 0.91 | KMT2A (0.36) | PAX8TSHRMEN1USP2POLB | |
| SCHEMBL16299450 | 0.91 | PTPN1 (0.36) | MEN1USP2POLBKMT2APTPN1 | |
| SCHEMBL10177687 | 0.91 | TSHR (0.41) | PAX8TSHRMEN1USP2POLB | |
| SCHEMBL16299428 | 0.91 | PTPN1 (0.40) | MEN1USP2POLBKMT2APTPN1 | |
| SCHEMBL15102707 | 0.91 | PTPN1 (0.36) | MEN1USP2POLBKMT2APTPN1 | |
| SCHEMBL19591034 | 0.90 | TSHR (0.38) | PAX8TSHRMEN1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179761-A1 | TARGETING LIPIDS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179761-A1 | TARGETING LIPIDS | LY96, ABHD10, APOB | PAX8 4314/4885TSHR 2940/4885MEN1 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.