Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5682510 | 0.81 | CYP2D6 (0.33) | ADRB2 | |
| SCHEMBL19210480 | 0.81 | CYP2D6 (0.48) | — | |
| SCHEMBL1583343 | 0.76 | CYP2D6 (0.43) | — | |
| SCHEMBL23855055 | 0.76 | TGFBR1 (0.36) | — | |
| SCHEMBL394954 | 0.76 | TGFBR1 (0.36) | — | |
| SCHEMBL1583801 | 0.75 | CA2 (0.33) | — | |
| SCHEMBL1290540 | 0.74 | ALDH1A1 (0.37) | — | |
| SCHEMBL4049397 | 0.74 | MAPT (0.43) | — | |
| SCHEMBL23855053 | 0.74 | MAPT (0.43) | — | |
| SCHEMBL3899245 | 0.74 | GRN (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |