Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21011740 | 0.77 | ALDH1A1 (0.34) | KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL10729999 | 0.74 | HPGD (0.42) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL17897165 | 0.73 | NQO2 (0.41) | KDM4EHPGDMAPTALDH1A1TDP1 | |
| SCHEMBL2306803 | 0.69 | KDM4E (0.48) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL6910193 | 0.69 | MEN1 (0.41) | KDM4EHPGDALDH1A1TDP1HTT | |
| SCHEMBL4427147 | 0.69 | KDM4E (0.47) | KDM4EHPGDMAPTNPSR1ALDH1A1 | |
| SCHEMBL31031292 | 0.67 | KDM4E (0.52) | KDM4EHPGDMAPTNPSR1ALDH1A1 | |
| SCHEMBL11645714 | 0.67 | MAOB (0.42) | KDM4EHPGDMAPTALDH1A1TDP1 | |
| SCHEMBL11645711 | 0.67 | MAOB (0.42) | KDM4EHPGDMAPTALDH1A1TDP1 | |
| SCHEMBL3689757 | 0.66 | KDM4E (0.40) | KDM4EHPGDMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160197275-A1 | EMITTER HAVING A CONDENSED RING SYSTEM | MERCK PATENT GMBH (DE) | 2016-07-07 | — | — | US | disclosed |
| US-20160197275-A1 | EMITTER HAVING A CONDENSED RING SYSTEM | MERCK PATENT GMBH (DE) | 2016-07-07 | — | — | US | disclosed |
| WO-2014094965-A2 | EMITTER HAVING A CONDENSED RING SYSTEM | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |