Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.37 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523395 | 0.73 | HPGD (0.46) | KDM4EHPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL19401265 | 0.72 | KDM4E (0.38) | KDM4EHPGDAKT1 | |
| SCHEMBL11883102 | 0.71 | PARP1 (0.40) | KDM4EHPGDTSHRACHEKMT2A | |
| SCHEMBL8143932 | 0.71 | NPC1 (0.44) | KDM4EHPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL31707307 | 0.71 | HPGD (0.40) | KDM4EHPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL20433970 | 0.71 | HPGD (0.36) | KDM4EHPGDAKT1TSHRALDH1A1 | |
| SCHEMBL28365976 | 0.71 | THRB (0.38) | KDM4EHPGDAKT1KMT2APTPN1 | |
| SCHEMBL21098969 | 0.71 | KDM4E (0.36) | KDM4EHPGDAKT1TSHRSMN1; SMN2 | |
| SCHEMBL18613076 | 0.68 | KDM4E (0.31) | KDM4EHPGD | |
| SCHEMBL22304415 | 0.68 | KDM4E (0.31) | KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100015076-A1 | POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF | EUDERMIC S.R.L. (IT) | 2010-01-21 | — | — | US | claimed |
| US-20100015076-A1 | POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF | EUDERMIC S.R.L. (IT) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100015076-A1 | POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF | KRT18, PRKDC, CKAP4 | KDM4E 1872/4885HPGD 670/4885AKT1 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.