Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 14/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15835871 | 1.00 | CHKA (0.56) | CHKAKDM4EALDH1A1RAB9ABCHE | |
| SCHEMBL25459981 | 0.98 | CHKA (0.53) | CHKAKDM4EALDH1A1RAB9ABCHE | |
| SCHEMBL17969131 | 0.90 | CHKA (0.57) | CHKAKDM4EALDH1A1RAB9AACHE | |
| SCHEMBL19646819 | 0.82 | CHKA (0.49) | CHKAKDM4EALDH1A1RAB9ABCHE | |
| SCHEMBL1108037 | 0.80 | CHKA (0.70) | CHKAKDM4EALDH1A1RAB9AACHE | |
| SCHEMBL25459980 | 0.79 | KDM4E (0.45) | CHKAKDM4EALDH1A1RAB9ABCHE | |
| SCHEMBL679626 | 0.78 | TSHR (0.56) | ALDH1A1 | |
| SCHEMBL9609757 | 0.78 | TSHR (0.56) | ALDH1A1 | |
| SCHEMBL14557472 | 0.77 | CHKA (0.67) | CHKAKDM4EALDH1A1RAB9AACHE | |
| SCHEMBL13851327 | 0.76 | CHKA (0.71) | CHKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290495-B2 | Tetracationic cyclophanes and their use in the sequestration of polyaromatic hydrocarbons by way of complexation | NORTHWESTERN UNIVERSITY (US) | 2016-03-22 | — | — | US | disclosed |
| US-9290495-B2 | Tetracationic cyclophanes and their use in the sequestration of polyaromatic hydrocarbons by way of complexation | NORTHWESTERN UNIVERSITY (US) | 2016-03-22 | — | — | US | disclosed |
| WO-2014100691-A1 | TETRACATIONIC CYCLOPHANES AND THEIR USE IN THE SEQUESTRATION OF POLYAROMATIC HYDROCARBONS BY WAY OF COMPLEXATION | NORTHWESTERN UNIVERSITY (US) | 2014-06-26 | — | — | WO | disclosed |
| US-20140179017-A1 | TETRACATIONIC CYCLOPHANES AND THEIR USE IN THE SEQUESTRATION OF POLYAROMATIC HYDROCARBONS BY WAY OF COMPLEXATION | ENERGY, UNITED STATES DEPARTMENT OF | 2014-06-26 | — | — | US | disclosed |
| US-20140179017-A1 | TETRACATIONIC CYCLOPHANES AND THEIR USE IN THE SEQUESTRATION OF POLYAROMATIC HYDROCARBONS BY WAY OF COMPLEXATION | ENERGY, UNITED STATES DEPARTMENT OF | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179017-A1 | TETRACATIONIC CYCLOPHANES AND THEIR USE IN THE SEQUESTRATION OF POLYAROMATIC HYDROCARBONS BY WAY OF COMPLEXATION | PRDX5, CYCS, PRDX1 | CHKA 4334/4885KDM4E 3246/4885ALDH1A1 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.