Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609757 | 1.00 | TSHR (0.56) | TSHRTRPA1ALDH1A1HRH3CES2 | |
| Water SCHEMBL11481683 | 0.97 | TSHR (0.53) | TSHRTRPA1ALDH1A1HRH3CES2 | |
| Methane SCHEMBL11480910 | 0.97 | TSHR (0.53) | TSHRTRPA1ALDH1A1HRH3CES2 | |
| SCHEMBL31377005 | 0.91 | ALDH1A1 (0.48) | TSHRTRPA1ALDH1A1HRH3CES2 | |
| SCHEMBL10049247 | 0.91 | TRPA1 (0.48) | TSHRTRPA1ALDH1A1HRH3CES2 | |
| SCHEMBL131361 | 0.89 | ALDH1A1 (0.67) | TSHRTRPA1ALDH1A1HRH3CES2 | |
| SCHEMBL71123 | 0.88 | ALDH1A1 (0.68) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL1374017 | 0.88 | ALDH1A1 (0.68) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL3362246 | 0.88 | ALDH1A1 (0.50) | TSHRTRPA1ALDH1A1HRH3CES2 | |
| SCHEMBL12187710 | 0.86 | HRH3 (0.46) | TSHRTRPA1ALDH1A1HRH3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118895116-A | Preparation method of oil-free phase temperature-resistant shearing-resistant fracturing fluid | 陕西志详拓实业有限公司 | 2024-11-05 | — | — | CN | claimed |
| CN-116284524-B | Super-crosslinked porous polyionic liquid with high ionic liquid content, preparation method and application | 合肥学院 | 2024-10-18 | — | — | CN | claimed |
| CN-118416947-A | High-selectivity ionic polymer catalytic material and preparation and application thereof | 福州大学 | 2024-08-02 | — | — | CN | claimed |
| CN-118344586-A | Ion covalent organic polymer material and preparation method and application thereof | 河北工程大学 | 2024-07-16 | — | — | CN | claimed |
| CN-118056852-A | Carbazolyl porous organic framework material and preparation method and application thereof | 右江民族医学院 | 2024-05-21 | — | — | CN | claimed |
| CN-114814041-B | Method for detecting brominated alkanes genotoxic impurities in telmisartan by adopting liquid chromatography-mass spectrometer | 浙江金立源药业有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-114907376-B | Molecular machine based on bi-m-benzene-32-crown-10 main body cave ether and preparation method thereof | 浙江大学杭州国际科创中心 | 2024-01-23 | — | — | CN | claimed |
| CN-116277696-B | Multilayer heat-insulating pipe and production process thereof | 河北乾海管道制造有限公司 | 2023-09-22 | — | — | CN | claimed |
| CN-116463697-A | Surface oxidation-resistant corrosion-resistant coating treatment process for semiconductor lead frame | 崇辉半导体(江门)有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-116463693-A | Treatment method for improving stability of semiconductor lead frame plating layer | 崇辉半导体(江门)有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-112245593-B | Stabilized cell penetrating peptide with hydrophobic side chain, preparation method and application | 西南交通大学 | 2022-05-13 | — | — | CN | claimed |
| CN-114380828-A | Synthetic method and application of perylene diimide-based bicyclic compound | 北京理工大学 | 2022-04-22 | — | — | CN | claimed |
| CN-113755475-A | ACE2 cyclopeptide mimic and application thereof in inhibiting new coronavirus | 西南医科大学附属中医医院 | 2021-12-07 | — | — | CN | claimed |
| CN-108358997-A | A kind of stabilization polypeptide that intracellular that modifying construction of strategy using double sulfosalts is reversible | 北京大学深圳研究生院 | 2018-08-03 | — | — | CN | claimed |
| EP-2181854-B1 | THERMOSENSITIVE RECORDING MATERIAL | NICCA CHEMICAL CO (JP) | 2012-08-15 | — | — | EP | claimed |
| US-7078465-B2 | Reacting paraformaldehyde with hydrogen bromide to form bis-bromomethyl ether as chemical intermediates; reacting biphenyl to form 4,4'-bis-(bromomethyl)-biphenyl, futher reacting with triethylphosphite to form 4,4'-bis-(diethylphosphonomethyl)-biphenyl; less hazardous, two stage processes | MAKHTESHIM CHEMICAL WORKS, LTD. (IL) | 2006-07-18 | — | — | US | claimed |
| US-20040242799-A1 | Reacting paraformaldehyde with hydrogen bromide to form bis-bromomethyl ether as chemical intermediates; reacting biphenyl to form 4,4'-bis-(bromomethyl)-biphenyl, futher reacting with triethylphosphite to form 4,4'-bis-(diethylphosphonomethyl)-biphenyl; less hazardous, two stage processes | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2004-12-02 | — | — | US | claimed |
| EP-1421050-A1 | PROCESS TO BROMOMETHYLATE AROMATIC COMPOUNDS | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 2004-05-26 | — | — | EP | claimed |
| WO-2003018518-A1 | PROCESS TO BROMOMETHYLATE AROMATIC COMPOUNDS | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2003-03-06 | — | — | WO | claimed |
| US-4070340-A | GREEN STRENGTH | POLYSAR LIMITED (CA) | 1978-01-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242799-A1 | Reacting paraformaldehyde with hydrogen bromide to form bis-bromomethyl ether as chemical intermediates; reacting biphenyl to form 4,4'-bis-(bromomethyl)-biphenyl, futher reacting with triethylphosphite to form 4,4'-bis-(diethylphosphonomethyl)-biphenyl; less hazardous, two stage processes | FGB, FHIT, PBRM1 | TSHR 1145/4885TRPA1 2369/4885ALDH1A1 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.