SCHEMBL15835964

SCHEMBL15835964

c1cnc2c(c1)oc1ccc(-c3ccc4oc5ccc(-c6ccc7oc8ccc(-c9ccc%10oc%11ccc(-c%12ccc%13oc%14cccnc%14c%13c%12)cc%11c%10c9)cc8c7c6)cc5c4c3)cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.44
MAPT P10636 2/20 0.44
MAPK14 Q16539 1/20 0.40
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
CASP3 P42574 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
KDM4E B2RXH2 3/20 0.38
RAB9A P51151 3/20 0.38
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 1/20 0.38
PLA2G2A P14555 3/20 0.37
PLA2G4A P47712 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
ATM Q13315 2/20 0.36
POLB P06746 1/20 0.36
NCOA1 Q15788 1/20 0.36
GRM4 Q14833 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16482063 1.00 NPC1 (0.44) NPC1MAPTMAPK14MEN1KMT2A
SCHEMBL15835963 1.00 NPC1 (0.44) NPC1MAPTMAPK14MEN1KMT2A
SCHEMBL15836114 0.97 NPC1 (0.42) NPC1MAPTMAPK14MEN1KMT2A
SCHEMBL15855216 0.95 PLA2G2A (0.41) NPC1MAPTMAPK14MEN1KMT2A
SCHEMBL15835955 0.95 PLA2G2A (0.41) NPC1MAPTMAPK14MEN1KMT2A
SCHEMBL15855443 0.95 PLA2G2A (0.41) NPC1MAPTMAPK14MEN1KMT2A
SCHEMBL15835973 0.95 PLA2G2A (0.41) NPC1MAPTMAPK14MEN1KMT2A
SCHEMBL15855242 0.95 PLA2G2A (0.41) NPC1MAPTMAPK14MEN1KMT2A
SCHEMBL15836044 0.95 NPC1 (0.51) NPC1MAPTMAPK14MEN1KMT2A
SCHEMBL15836017 0.95 PLA2G2A (0.41) NPC1MAPTMAPK14MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-9978952-B2 Fused heterocyclic aromatic derivative, organic electroluminescence element material, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-22 US disclosed
US-9978952-B2 Fused heterocyclic aromatic derivative, organic electroluminescence element material, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-22 US disclosed
US-20140175419-A1 FUSED HETEROCYCLIC AROMATIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-06-26 US disclosed
US-20140175419-A1 FUSED HETEROCYCLIC AROMATIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 NPC1 469/4885MAPT 1926/4885MAPK14 3057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.