SCHEMBL15838

SCHEMBL15838

COc1ccc(C=CC(=O)OC(C)C)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.71
AKR1B10 O60218 1/20 0.71
CA1 P00915 1/20 0.71
CA2 P00918 1/20 0.71
AKR1B1 P15121 1/20 0.71
CA7 P43166 1/20 0.71
CA9 Q16790 1/20 0.71
CA14 Q9ULX7 1/20 0.71
F3 P13726 2/20 0.64
LMNA P02545 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
THRB P10828 1/20 0.62
ATM Q13315 1/20 0.62
GSK3B P49841 2/20 0.60
MAPT P10636 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HDAC3 O15379 2/20 0.58
HDAC1 Q13547 2/20 0.58
HDAC2 Q92769 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL342878 1.00 CA12 (0.71) CA12AKR1B10CA1CA2AKR1B1
Water SCHEMBL8001684 0.98 CA12 (0.69) CA12AKR1B10CA1CA2AKR1B1
Acetic Acid SCHEMBL28512748 0.95 CA12 (0.65) CA12AKR1B10CA1CA2AKR1B1
Isopropyl 3-(4-Isopropylphenyl)Acrylate SCHEMBL27759962 0.93 CA12 (0.61) CA12AKR1B10CA1CA2AKR1B1
Propionic Acid SCHEMBL28056113 0.91 CA12 (0.60) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL20943451 0.88 LMNA (0.68) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL27581575 0.87 F3 (0.60) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL19244483 0.87 CA12 (0.71) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL19244482 0.87 CA12 (0.71) CA12AKR1B10CA1CA2AKR1B1
Amiloxate SCHEMBL3136516 0.87 LMNA (0.88) CA12AKR1B10CA1CA2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5884 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025125748-A1 COSMETIC COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION COMPRISING A COMBINATION OF LIPOSOLUBLE POLYMER BASED ON MODIFIED PULLULAN AND WATER-SOLUBLE POLYMER LVMH RECHERCHE (FR) 2025-06-19 WO claimed
WO-2025125749-A1 COSMETIC COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION HAVING A HIGH NON-VOLATILE OIL CONTENT AND COMPRISING A LIPOSOLUBLE POLYMER BASED ON MODIFIED PULLULAN LVMH RECHERCHE (FR) 2025-06-19 WO claimed
US-20240390237-A1 SOLID COSMETIC SHISEIDO COMPANY, LTD. (JP) 2024-11-28 US claimed
CN-117017794-A Water-in-oil emulsion 莱雅公司 2023-11-10 CN claimed
CN-113272021-B Water-in-oil type emulsified cosmetic for sunscreening 花王株式会社 2023-07-28 CN claimed
CN-116456956-A Solid cosmetic material 株式会社资生堂 2023-07-18 CN claimed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN claimed
CN-114828816-A Composition for conditioning keratin fibers 莱雅公司 2022-07-29 CN claimed
WO-2022138538-A1 SOLID COSMETIC 株式会社 資生堂 2022-06-30 WO claimed
EP-3154510-B1 COMPOSITION FOR PROTECTING KERATIN MATERIALS FROM SUN OREAL (FR) 2022-01-19 EP claimed
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL, S.A. (FR) 2004-04-01 US claimed
EP-1364939-A1 UTILIZATION FOR IMPROVING STABILITY OF UV-ABSORBING SUBSTANCES, UV-ABSORBERS AND COSMETICS The Nisshin OilliO, Ltd. (JP) 2003-11-26 EP claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
US-6007846-A COSMETIC GEL COMPRISING SKIN-MOISTURIZING SURFACTANT, PH ADJUSTER, PERSERVATIVE, ANTIOXIDANT, DILUENT, SUSPENDED SHAPED GLITTER PARTICLES TOWNLEY JEWELRY, INC. (US) 1999-12-28 US claimed
US-5853706-A Scented hair gel having particulate matter in the form of glitter TOWNLEY JEWELRY, INC. (US) 1998-12-29 US claimed
US-5843415-A Scented hair gel having particulate matter in the form of glitter with predetermined shapes TOWNLEY JEWELRY, INC. (US) 1998-12-01 US claimed
US-5820884-A SURFACTANT; PRESERVATIVE SYSTEM; ANTIOXIDANT(S); LIGHT STABILIZERS(S); SUSPENDED PARTICULATE MATTER FOR COSMETIC ORNAMENTATION TOWNLEY JEWELRY, INC. (US) 1998-10-13 US claimed
EP-0308543-B1 COMPOSITIONS FOR EXTERNAL APPLICATION Sansho Seiyaku Co., Ltd. (JP) 1993-09-22 EP claimed
US-4948577-A KOJIC ACID AND 4-/1,1-DIMETHYLETHYL/-4'-METHOXY DIBENZOYLMETHANE; PREVENT COLORING OF SKIN WHEN EXPOSED TO ULTRAVIOLET LIGHT SANSHO SEIYAKU CO., LTD. (JP) 1990-08-14 US claimed
EP-0308543-A1 Compositions for external application Sansho Seiyaku Co., Ltd. (JP) 1989-03-29 EP claimed