SCHEMBL342878

SCHEMBL342878

COc1ccc(/C=C/C(=O)OC(C)C)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.71
AKR1B10 O60218 1/20 0.71
CA1 P00915 1/20 0.71
CA2 P00918 1/20 0.71
AKR1B1 P15121 1/20 0.71
CA7 P43166 1/20 0.71
CA9 Q16790 1/20 0.71
CA14 Q9ULX7 1/20 0.71
F3 P13726 2/20 0.64
LMNA P02545 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
THRB P10828 1/20 0.62
ATM Q13315 1/20 0.62
GSK3B P49841 2/20 0.60
MAPT P10636 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HDAC3 O15379 2/20 0.58
HDAC1 Q13547 2/20 0.58
HDAC2 Q92769 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15838 1.00 CA12 (0.71) CA12AKR1B10CA1CA2AKR1B1
Water SCHEMBL8001684 0.98 CA12 (0.69) CA12AKR1B10CA1CA2AKR1B1
Acetic Acid SCHEMBL28512748 0.95 CA12 (0.65) CA12AKR1B10CA1CA2AKR1B1
Isopropyl 3-(4-Isopropylphenyl)Acrylate SCHEMBL27759962 0.93 CA12 (0.61) CA12AKR1B10CA1CA2AKR1B1
Propionic Acid SCHEMBL28056113 0.91 CA12 (0.60) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL20943451 0.88 LMNA (0.68) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL27581575 0.87 F3 (0.60) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL19244483 0.87 CA12 (0.71) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL19244482 0.87 CA12 (0.71) CA12AKR1B10CA1CA2AKR1B1
Amiloxate SCHEMBL3136516 0.87 LMNA (0.88) CA12AKR1B10CA1CA2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2247 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113272021-B Water-in-oil type emulsified cosmetic for sunscreening 花王株式会社 2023-07-28 CN claimed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN claimed
CN-105997532-B Oil-in-water type emulsion cosmetic 花王株式会社 2020-09-22 CN claimed
EP-2662068-B1 OIL-IN-WATER EMULSION COMPOSITION KAO CORP (JP) 2017-07-05 EP claimed
US-9314488-B2 Cellular extracts REGENICS AS (NO) 2016-04-19 US claimed
CN-104780900-A Oil-in-water emulsion composition KAO CORP 2015-07-15 CN claimed
CN-103298443-B Oil-in-water type emulsion composition KAO CORP 2015-06-17 CN claimed
CN-104510628-A Household paper GOLD HONG YE PAPER CO LTD 2015-04-15 CN claimed
US-8993494-B2 Compositions comprising reverse micelles and methods for their use EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-03-31 US claimed
US-8877253-B2 Cellular extracts REGENICS AS (NO) 2014-11-04 US claimed
CN-1753968-A Antioxidant composition and external composition MITSUBISHI CORP (JP) 2006-03-29 CN claimed
EP-1595936-A1 ANTIOXIDATIVE COMPOSITION AND COMPOSITION FOR EXTERNAL USE MITSUBISHI CORPORATION (JP) 2005-11-16 EP claimed
CN-1223574-C Use of ultraviolet absorber for enhancing stability of ultraviolet absorber, ultraviolet absorber and cosmetic NISSHIN OIL MILLS LTD (JP) 2005-10-19 CN claimed
CN-1491205-A Use of ultraviolet absorber for enhancing stability of ultraviolet absorber, ultraviolet absorber and cosmetic 日清奥利友株式会社 2004-04-21 CN claimed
US-20040067207-A1 Utilization for improving stability of uv-absorbing substances, uv-absorbers and cosmetics NISSHIN OILLIO GROUP, LTD., THE (JP) 2004-04-08 US claimed
EP-1364939-A1 UTILIZATION FOR IMPROVING STABILITY OF UV-ABSORBING SUBSTANCES, UV-ABSORBERS AND COSMETICS The Nisshin OilliO, Ltd. (JP) 2003-11-26 EP claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
EP-0308543-B1 COMPOSITIONS FOR EXTERNAL APPLICATION Sansho Seiyaku Co., Ltd. (JP) 1993-09-22 EP claimed
US-4948577-A KOJIC ACID AND 4-/1,1-DIMETHYLETHYL/-4'-METHOXY DIBENZOYLMETHANE; PREVENT COLORING OF SKIN WHEN EXPOSED TO ULTRAVIOLET LIGHT SANSHO SEIYAKU CO., LTD. (JP) 1990-08-14 US claimed
EP-0308543-A1 Compositions for external application Sansho Seiyaku Co., Ltd. (JP) 1989-03-29 EP claimed