Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15835743 | 0.93 | HPGD (0.41) | NPC1RAB9AHPGDNPSR1PPARG | |
| SCHEMBL15839273 | 0.90 | RAF1 (0.46) | KMT2ARAF1 | |
| SCHEMBL15839350 | 0.89 | PPARA (0.44) | MEN1KMT2AHPGDNPSR1PPARA | |
| SCHEMBL14474214 | 0.89 | ADRB2 (0.47) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL15835763 | 0.88 | HPGD (0.44) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL15839330 | 0.86 | HCRTR2 (0.40) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL15839347 | 0.86 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL17865381 | 0.84 | HPGD (0.57) | HPGDNPSR1PPARGEPHX2NR1H4 | |
| SCHEMBL15839278 | 0.84 | SCN9A (0.42) | PPARGPPARARAF1 | |
| SCHEMBL14474217 | 0.83 | RAF1 (0.49) | TRPV1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946270-B2 | Amido-pyridyl ether compounds and compositions and their use against parasites | MERIAL LIMITED (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140179746-A1 | AMIDO-PYRIDYL ETHER COMPOUNDS AND COMPOSITIONS AND THEIR USE AGAINST PARASITES | MERIAL LIMITED (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179746-A1 | AMIDO-PYRIDYL ETHER COMPOUNDS AND COMPOSITIONS AND THEIR USE AGAINST PARASITES | ARG1, PRMT9, H1-10 | MEN1 2431/4885KMT2A 3280/4885NPC1 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.