Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR5A | P47898 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840202 | 1.00 | PDK2 (0.39) | PDK2MAOATDO2HTR2BHTR5A | |
| SCHEMBL18156839 | 0.91 | TDO2 (0.36) | PDK2MAOATDO2HTR2BHTR5A | |
| SCHEMBL15840120 | 0.89 | PDK2 (0.36) | PDK2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15824466 | 0.88 | KIF11 (0.45) | MAOATDO2KIF11PGRGABRP | |
| SCHEMBL31632211 | 0.88 | KIF11 (0.45) | MAOATDO2KIF11PGRGABRP | |
| SCHEMBL29506370 | 0.88 | KIF11 (0.45) | MAOATDO2KIF11PGRGABRP | |
| SCHEMBL20199544 | 0.87 | KIF11 (0.44) | MAOATDO2KIF11PGRGABRP | |
| SCHEMBL15840146 | 0.87 | KIF11 (0.46) | MAOATDO2KIF11PGRGABRP | |
| SCHEMBL17379810 | 0.86 | PIM3 (0.33) | PDK2MAOAKIF11PGRGABRP | |
| SCHEMBL15840241 | 0.83 | KIF11 (0.50) | MAOAKIF11PGRGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227528-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2019-03-12 | — | — | US | disclosed |
| EP-2935276-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-20150337197-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150337197-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| WO-2014094963-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10227528-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | PDK2 1078/4885MAOA 399/4885TDO2 1798/4885 |
| US-20150337197-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EML4, L1CAM | PDK2 1107/4885MAOA 320/4885TDO2 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.