Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237063 | 0.84 | IDO1 (0.47) | ALOX15CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6126088 | 0.81 | ALOX15 (0.41) | ALOX15CYP1A2CYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL31497138 | 0.79 | ALOX15 (0.36) | ALOX15CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4169345 | 0.78 | TAAR1 (0.46) | CYP1A2CYP3A4CYP2C19NPSR1TRPA1 | |
| SCHEMBL16379379 | 0.78 | ALOX15 (0.40) | ALOX15CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4161045 | 0.78 | TAAR1 (0.46) | CYP1A2CYP3A4CYP2C19NPSR1TRPA1 | |
| SCHEMBL4178223 | 0.78 | TAAR1 (0.46) | CYP1A2CYP3A4CYP2C19NPSR1TRPA1 | |
| SCHEMBL336710 | 0.77 | PSEN1 (0.39) | GABRA1GABRG2GABRB3GABRB2PSEN1 | |
| SCHEMBL31185565 | 0.77 | PSEN1 (0.39) | GABRA1GABRG2GABRB3GABRB2PSEN1 | |
| SCHEMBL15822166 | 0.76 | ALOX15 (0.45) | ALOX15CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935296-B1 | CATALYST | BOREALIS AG (AT) | 2017-11-15 | — | — | EP | disclosed |
| US-20150329653-A1 | CATALYST | BOREALIS AG (AT) | 2015-11-19 | — | — | US | disclosed |
| WO-2014096282-A1 | CATALYST | BOREALIS AG (AT) | 2014-06-26 | — | — | WO | disclosed |