SCHEMBL15822166

SCHEMBL15822166

Cc1ccc(CC(C)C(=O)Cl)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
MC4R P32245 4/20 0.42
ACACB O00763 1/20 0.39
MMP2 P08253 1/20 0.38
ADAM17 P78536 1/20 0.38
HPGD P15428 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
ALOX12 P18054 1/20 0.36
HDAC8 Q9BY41 2/20 0.36
CYP2C9 P11712 1/20 0.36
EPHX1 P07099 1/20 0.35
P2RX3 P56373 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390329 1.00 ALOX15 (0.45) ALOX15CYP3A4CYP1A2CYP2D6CYP2C19
SCHEMBL17403185 0.82 MMP2 (0.37) ALOX15CYP3A4CYP1A2CYP2D6CYP2C19
SCHEMBL15808875 0.82 MMP2 (0.40) ALOX15MMP2ADAM17HPGDMEN1
SCHEMBL6126088 0.78 ALOX15 (0.41) ALOX15CYP3A4CYP1A2CYP2D6CYP2C19
SCHEMBL1454624 0.77 NPC1 (0.46) LMNARAB9AKMT2A
SCHEMBL15840454 0.76 ALOX15 (0.41) ALOX15CYP3A4CYP1A2CYP2D6CYP2C19
SCHEMBL2900705 0.75 USP2 (0.47) ALOX15CYP3A4HPGDKDM4EMEN1
SCHEMBL30225671 0.75 USP2 (0.47) ALOX15CYP3A4HPGDKDM4EMEN1
SCHEMBL13743627 0.75 USP2 (0.47) ALOX15CYP3A4HPGDKDM4EMEN1
SCHEMBL2900708 0.75 USP2 (0.47) ALOX15CYP3A4HPGDKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11981801-B2 Polypropylene composition BOREALIS AG (AT) 2024-05-14 US disclosed
US-20230242748-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2023-08-03 US disclosed
US-20230242748-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2023-08-03 US disclosed
US-20230242748-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2023-08-03 US disclosed
CN-110770264-B Process for preparing heterophasic propylene copolymers 博里利斯股份公司 2022-10-14 CN disclosed
CN-110177798-B Catalyst and process for preparing same 博里利斯股份公司 2022-08-30 CN disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
CN-110741039-B Polypropylene composition 博里利斯股份公司 2022-02-18 CN disclosed
US-11078304-B2 Process for preparing heterophasic propylene copolymers BOREALIS AG (AT) 2021-08-03 US disclosed
WO-2019007655-A1 PROCESS FOR PREPARING HETEROPHASIC PROPYLENE COPOLYMERS BOREALIS AG (AT) 2019-01-10 WO disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed
EP-3301098-A1 PROCESS FOR THE PREPARATION OF A LIGAND FOR A CATALYST Borealis AG (AT) 2018-04-04 EP disclosed
EP-3301098-A1 PROCESS FOR THE PREPARATION OF A LIGAND FOR A CATALYST Borealis AG (AT) 2018-04-04 EP disclosed
EP-2935296-B1 CATALYST BOREALIS AG (AT) 2017-11-15 EP disclosed
EP-2935296-B1 CATALYST BOREALIS AG (AT) 2017-11-15 EP disclosed
US-20150329653-A1 CATALYST BOREALIS AG (AT) 2015-11-19 US disclosed
US-20150329653-A1 CATALYST BOREALIS AG (AT) 2015-11-19 US disclosed
EP-2935296-A1 CATALYST Borealis AG (AT) 2015-10-28 EP disclosed
WO-2014096282-A1 CATALYST BOREALIS AG (AT) 2014-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352376-B2 Catalysts SIGMAR1, H1-2, SFN ALOX15 3876/4885CYP3A4 1978/4885CYP1A2 904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.