SCHEMBL15840503

SCHEMBL15840503

C/C(=N\c1c(C(C)C)cccc1C(C)C)c1cccc(/C(C)=N/C2CCCCC2)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 1/20 0.41
RAB9A P51151 3/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
SIGMAR1 Q99720 3/20 0.33
POLB P06746 1/20 0.31
MEN1 O00255 1/20 0.30
GFER P55789 1/20 0.30
KMT2A Q03164 1/20 0.30
HIF1A Q16665 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1002830 0.84 GABRA1 (0.41) ALOX15SMN1; SMN2SIGMAR1KMT2AHIF1A
SCHEMBL808792 0.84 GABRA1 (0.41) ALOX15SMN1; SMN2SIGMAR1KMT2AHIF1A
SCHEMBL4887039 0.84 ALDH1A1 (0.54) ALDH1A1ALOX15RAB9AMAPTSMN1; SMN2
SCHEMBL4887030 0.84 ALDH1A1 (0.54) ALDH1A1ALOX15RAB9AMAPTSMN1; SMN2
SCHEMBL14804875 0.83 METAP2 (0.30) MEN1KMT2A
SCHEMBL27608902 0.82 GABRA1 (0.40) ALOX15SIGMAR1KMT2AHIF1AGABRA1
SCHEMBL5589413 0.82 GABRA1 (0.40) ALOX15SIGMAR1KMT2AHIF1AGABRA1
Hydrochloric Acid SCHEMBL7173330 0.81 ALDH1A1 (0.51) ALDH1A1ALOX15RAB9AMAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL7183213 0.81 ALDH1A1 (0.51) ALDH1A1ALOX15RAB9AMAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL1575753 0.81 GABRA1 (0.39) ALOX15SIGMAR1KMT2AHIF1AGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935362-B1 PROCESS FOR THE PREPARATION OF (CO) POLYMERS OF CONJUGATED DIENES IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A BIS-IMINO-PYRIDINE COMPLEX OF COBALT VERSALIS SPA (IT) 2021-01-20 EP disclosed
US-9475897-B2 Process for the preparation of (co)polymers of conjugated dienes in the presence of a catalytic system comprising a bis-imino-pyridine complex of cobalt VERSALIS S.P.A. (IT) 2016-10-25 US disclosed
US-9475897-B2 Process for the preparation of (co)polymers of conjugated dienes in the presence of a catalytic system comprising a bis-imino-pyridine complex of cobalt VERSALIS S.P.A. (IT) 2016-10-25 US disclosed
US-20150329654-A1 PROCESS FOR THE PREPARATION OF (CO) POLYMERS OF CONJUGATED DIENES IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A BIS-IMINO-PYRIDINE COMPLEX OF COBALT VERSALIS S.P.A. (IT) 2015-11-19 US disclosed
US-20150329654-A1 PROCESS FOR THE PREPARATION OF (CO) POLYMERS OF CONJUGATED DIENES IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A BIS-IMINO-PYRIDINE COMPLEX OF COBALT VERSALIS S.P.A. (IT) 2015-11-19 US disclosed
WO-2014097245-A1 PROCESS FOR THE PREPARATION OF (CO) POLYMERS OF CONJUGATED DIENES IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A BIS-IMINO-PYRIDINE COMPLEX OF COBALT VERSALIS S.P.A. (IT) 2014-06-26 WO disclosed