Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.60 |
| ▸ | SGMS1 | Q86VZ5 | 4/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27496854 | 0.85 | PPARG (0.83) | ALDH1A1KMT2APPARGPOLBLMNA | |
| SCHEMBL14096626 | 0.84 | RAB9A (1.00) | RAB9AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15840617 | 0.82 | GPR55 (0.66) | ALDH1A1KMT2APPARGLMNAMEN1 | |
| SCHEMBL15840624 | 0.81 | ALDH1A1 (1.00) | RAB9AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15840505 | 0.81 | GPR55 (0.65) | RAB9AALDH1A1KMT2APPARGPOLB | |
| SCHEMBL7109149 | 0.80 | ALDH1A1 (1.00) | ALDH1A1POLBSGMS1SMN1; SMN2 | |
| SCHEMBL11113173 | 0.79 | ALDH1A1 (0.79) | ALDH1A1KMT2APPARGPOLBLMNA | |
| SCHEMBL25132370 | 0.79 | ALDH1A1 (0.71) | ALDH1A1KMT2APPARGLMNAMEN1 | |
| SCHEMBL15840638 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KMT2APPARGPOLBLMNA | |
| SCHEMBL15840535 | 0.79 | GPR55 (0.67) | RAB9AALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
| CN-102994611-A | Establishing method for drug screening model of high-throughput Japanese encephalitis virus helicase inhibitor | UNIV HUAZHONG AGRICULTURAL | 2013-03-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | RAB9A 2629/4885ALDH1A1 4348/4885CYP3A4 4074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.