Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840757 | 0.86 | KMT2A (0.62) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM | |
| SCHEMBL15840827 | 0.82 | MAPK1 (0.59) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM | |
| SCHEMBL15840817 | 0.82 | MAPK1 (0.70) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM | |
| SCHEMBL15840596 | 0.79 | MAPT (0.63) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM | |
| SCHEMBL15840598 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM | |
| SCHEMBL22853716 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM | |
| SCHEMBL15840763 | 0.75 | ALDH1A1 (0.62) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM | |
| SCHEMBL15840784 | 0.73 | MAPT (0.56) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM | |
| SCHEMBL15840582 | 0.73 | ALPL (0.65) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM | |
| SCHEMBL15840599 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KMT2ASMN1; SMN2CREBBPPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | ALDH1A1 4348/4885KMT2A 3667/4885SMN1; SMN2 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.