Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | STAT3 | P40763 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | STAT1 | P42224 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840817 | 0.86 | MAPK1 (0.70) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM | |
| SCHEMBL15840588 | 0.86 | ALDH1A1 (0.60) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM | |
| SCHEMBL15840827 | 0.84 | MAPK1 (0.59) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM | |
| SCHEMBL15840596 | 0.84 | MAPT (0.63) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM | |
| SCHEMBL15840598 | 0.83 | ALDH1A1 (0.59) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM | |
| SCHEMBL22853716 | 0.81 | ALDH1A1 (0.52) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM | |
| SCHEMBL15840763 | 0.79 | ALDH1A1 (0.62) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM | |
| SCHEMBL15840784 | 0.78 | MAPT (0.56) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM | |
| SCHEMBL15840582 | 0.77 | ALPL (0.65) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM | |
| SCHEMBL15840599 | 0.76 | ALDH1A1 (0.50) | KMT2AALDH1A1SMN1; SMN2CREBBPPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | KMT2A 3667/4885ALDH1A1 4348/4885SMN1; SMN2 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.