Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.69 |
| ▸ | ALPL | P05186 | 1/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | ALPG | P10696 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840582 | 0.79 | ALPL (0.65) | STAT3ALPLALPIALPGTP53 | |
| SCHEMBL15840676 | 0.77 | STAT3 (1.00) | STAT3TP53STAT1MAPTSMN1; SMN2 | |
| SCHEMBL15840753 | 0.76 | STAT3 (0.71) | STAT3TP53STAT1MAPTSMN1; SMN2 | |
| SCHEMBL15840657 | 0.76 | STAT3 (0.72) | STAT3ALPLALPIALPGTP53 | |
| SCHEMBL15840610 | 0.71 | STAT3 (0.60) | STAT3ALPLALPIALPGTP53 | |
| SCHEMBL9878449 | 0.69 | MAPT (0.66) | ALPLALPIALPGTP53MAPT | |
| SCHEMBL23021122 | 0.69 | MAPT (0.57) | STAT3ALPLALPIALPGTP53 | |
| SCHEMBL15840835 | 0.68 | MAPT (0.81) | STAT3ALPLTP53STAT1MAPT | |
| SCHEMBL2495418 | 0.67 | MAPT (0.49) | STAT3ALPLALPIALPGTP53 | |
| SCHEMBL9878904 | 0.67 | MAPT (0.75) | ALPLALPIALPGTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | STAT3 429/4885ALPL 4629/4885ALPI 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.