Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | STAT1 | P42224 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840676 | 0.81 | STAT3 (1.00) | STAT3TP53STAT1MAPTPOLB | |
| SCHEMBL15840774 | 0.80 | MAPT (0.61) | STAT3MAPTHSD17B10ALDH1A1KMT2A | |
| SCHEMBL838117 | 0.80 | ALDH1A1 (0.47) | STAT3TP53STAT1MAPTPOLB | |
| SCHEMBL15840753 | 0.78 | STAT3 (0.71) | STAT3TP53STAT1MAPTPOLB | |
| SCHEMBL15836645 | 0.78 | CREBBP (0.59) | STAT3MAPTHSD17B10ALDH1A1KMT2A | |
| SCHEMBL15840602 | 0.76 | STAT3 (0.69) | STAT3TP53STAT1MAPTPOLB | |
| SCHEMBL15840610 | 0.75 | STAT3 (0.60) | STAT3TP53STAT1MAPTPOLB | |
| SCHEMBL837878 | 0.71 | TDP2 (0.74) | STAT3MAPTPOLBHSD17B10ALDH1A1 | |
| SCHEMBL30917202 | 0.71 | TDP2 (0.74) | STAT3MAPTPOLBHSD17B10ALDH1A1 | |
| SCHEMBL15840835 | 0.71 | MAPT (0.81) | STAT3TP53STAT1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | STAT3 429/4885TP53 230/4885STAT1 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.