Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | AKT1 | P31749 | 1/20 | 0.60 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401402 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KMT2AALOX12LMNATDP1 | |
| SCHEMBL287025 | 0.76 | AKT1 (1.00) | ALDH1A1KMT2AMEN1MAPTPKM | |
| SCHEMBL15840511 | 0.76 | KMT2A (1.00) | ALDH1A1KMT2AALOX12LMNATDP1 | |
| SCHEMBL11893078 | 0.75 | AKT1 (0.80) | ALDH1A1KMT2AMEN1PKMAKT1 | |
| SCHEMBL15840653 | 0.75 | KMT2A (0.85) | ALDH1A1KMT2AALOX12LMNATDP1 | |
| SCHEMBL12173925 | 0.74 | ALDH1A1 (0.64) | ALDH1A1KMT2AALOX12LMNATDP1 | |
| SCHEMBL15840526 | 0.74 | KMT2A (1.00) | ALDH1A1KMT2AALOX12LMNATDP1 | |
| SCHEMBL15840646 | 0.73 | KMT2A (1.00) | ALDH1A1KMT2AALOX12LMNATDP1 | |
| SCHEMBL12173922 | 0.73 | ALDH1A1 (0.63) | ALDH1A1KMT2AALOX12LMNATDP1 | |
| SCHEMBL5407138 | 0.72 | MEN1 (1.00) | ALDH1A1KMT2AMEN1PKMAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | ALDH1A1 4348/4885KMT2A 3667/4885ALOX12 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.