Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840615 | 0.88 | NPSR1 (0.73) | NPSR1POLBALDH1A1ALOX12MEN1 | |
| SCHEMBL15840656 | 0.86 | ALDH1A1 (0.78) | NPSR1POLBALDH1A1ALOX12MEN1 | |
| SCHEMBL15840626 | 0.85 | NPSR1 (0.69) | NPSR1POLBALDH1A1ALOX12MEN1 | |
| SCHEMBL15840667 | 0.83 | ALDH1A1 (1.00) | NPSR1POLBALDH1A1ALOX12MEN1 | |
| SCHEMBL15840616 | 0.82 | ALDH1A1 (0.64) | NPSR1POLBALDH1A1ALOX12MEN1 | |
| SCHEMBL15840622 | 0.81 | ALDH1A1 (1.00) | NPSR1POLBALDH1A1ALOX12MEN1 | |
| SCHEMBL17066604 | 0.81 | ALDH1A1 (0.63) | NPSR1POLBALDH1A1ALOX12MEN1 | |
| SCHEMBL15840671 | 0.81 | LMNA (0.68) | NPSR1POLBALDH1A1ALOX12MEN1 | |
| SCHEMBL13453831 | 0.79 | ALDH1A1 (0.62) | NPSR1POLBALDH1A1ALOX12MEN1 | |
| SCHEMBL13454367 | 0.79 | ALDH1A1 (0.68) | NPSR1POLBALDH1A1ALOX12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | NPSR1 3556/4885POLB 3390/4885ALDH1A1 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.