Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066606 | 0.89 | GPR55 (0.56) | ALDH1A1ALOX12MAPTLMNASMN1; SMN2 | |
| SCHEMBL13454367 | 0.87 | ALDH1A1 (0.68) | ALDH1A1ALOX12MAPTLMNASMN1; SMN2 | |
| SCHEMBL17066608 | 0.87 | NPSR1 (0.68) | ALDH1A1ALOX12MAPTMEN1KMT2A | |
| SCHEMBL13453831 | 0.87 | ALDH1A1 (0.62) | ALDH1A1ALOX12MAPTLMNASMN1; SMN2 | |
| SCHEMBL17066585 | 0.87 | MAPT (0.54) | ALDH1A1ALOX12MAPTLMNASMN1; SMN2 | |
| SCHEMBL17066679 | 0.86 | GPR55 (0.56) | ALDH1A1ALOX12MAPTLMNASMN1; SMN2 | |
| SCHEMBL17066643 | 0.85 | TP53 (0.60) | ALDH1A1ALOX12MAPTLMNASMN1; SMN2 | |
| SCHEMBL13453838 | 0.85 | ALDH1A1 (0.66) | ALDH1A1ALOX12MAPTLMNASMN1; SMN2 | |
| SCHEMBL17066561 | 0.85 | ALDH1A1 (0.66) | ALDH1A1ALOX12MAPTLMNASMN1; SMN2 | |
| SCHEMBL17066602 | 0.85 | ALDH1A1 (0.68) | ALDH1A1ALOX12MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |