SCHEMBL15840994

SCHEMBL15840994

CC1(C)CC(C)(C)c2c1c1ccccc1c1nc(=O)ccn21

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 6/20 0.34
PARP1 P09874 1/20 0.32
MTOR P42345 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15840995 0.80 KDM4E (0.31)
SCHEMBL15840934 0.80 PRKDC (0.43) PRKDCPARP1MTOR
SCHEMBL18015544 0.78 P2RX7 (0.31)
SCHEMBL15840892 0.75 KDM4E (0.31)
SCHEMBL19794383 0.73
SCHEMBL18015543 0.73 JAK2 (0.31)
SCHEMBL21477442 0.71 PRKDC (0.30) PRKDC
SCHEMBL17298918 0.71 HSD11B1 (0.46)
SCHEMBL19794407 0.69 PRKDC (0.33) PRKDCMTOR
SCHEMBL15840895 0.69 KMT2A (0.34) PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935291-B1 IRIDIUM COMPLEXES USED IN OLIGOMERS, POLYMERS OR DENDRIMERS IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-10-16 EP disclosed
US-20150349277-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2015-12-03 US disclosed
US-20150349277-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2015-12-03 US disclosed
WO-2014094960-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150349277-A1 METAL COMPLEXES SOD1, AP1M1, AP3M1 PRKDC 3860/4885PARP1 1422/4885MTOR 4584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.