Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15845417 | 0.88 | ALDH1A1 (0.41) | PGRMAPTHPGDMAPK1CFTR | |
| SCHEMBL15845411 | 0.85 | PGR (0.38) | PGRHSD11B1MAPTPOLBSIRT2 | |
| SCHEMBL15845403 | 0.85 | PGR (0.38) | PGRHSD11B1MAPTPOLBSIRT2 | |
| SCHEMBL15845408 | 0.85 | MAPT (0.40) | PGRHSD11B1MAPTPOLBHPGD | |
| SCHEMBL19501151 | 0.80 | L3MBTL1 (0.40) | HSD11B1MAPTPOLBHPGDMAPK1 | |
| SCHEMBL15845415 | 0.76 | ALDH1A1 (0.41) | PGRPOLBCFTRMEN1KMT2A | |
| SCHEMBL15845375 | 0.76 | ALDH1A1 (0.41) | PGRMAPTPOLBCFTRMEN1 | |
| SCHEMBL25491687 | 0.76 | MAPT (0.40) | HSD11B1MAPTPOLBHPGDMAPK1 | |
| SCHEMBL15845382 | 0.74 | KMT2A (0.39) | PGRHSD11B1MAPTPOLBHPGD | |
| SCHEMBL15845405 | 0.72 | ALDH1A1 (0.40) | PGRMAPTPOLBHPGDSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140369931-A1 | PSMA-BINDING AGENTS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-12-18 | — | — | US | disclosed |
| WO-2014104665-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME | 주식회사 두산 (KR) | 2014-07-03 | — | — | WO | disclosed |
| WO-2014104665-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME | 주식회사 두산 (KR) | 2014-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140369931-A1 | PSMA-BINDING AGENTS AND USES THEREOF | KLK3, FOLH1, DNPEP | PGR 254/4885HSD11B1 4059/4885MAPT 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.