Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2265666 | 0.77 | PIK3CD (0.44) | P2RX7 | |
| SCHEMBL1817592 | 0.66 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL2487318 | 0.65 | LMNA (0.34) | RIPK1 | |
| SCHEMBL5171227 | 0.65 | CNR1 (0.35) | FPR2CNR2BDKRB2 | |
| SCHEMBL892512 | 0.64 | CHRM5 (0.41) | P2RX7FPR2GRM2CNR2BDKRB2 | |
| SCHEMBL3325115 | 0.64 | HTT (0.39) | OPRM1FPR2CYP1A2GRM2 | |
| SCHEMBL1942989 | 0.62 | TSHR (0.41) | KCNH2 | |
| SCHEMBL12776319 | 0.62 | RAB9A (0.50) | — | |
| SCHEMBL168896 | 0.61 | POLB (0.32) | — | |
| SCHEMBL15720462 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |